Evidence map›Paper›PMID 37783822›Full record

ReviewNature reviews. Chemistry2023

Applications of macrocycle-based solid-state host-guest chemistry.

Huangtianzhi Zhu, Liya Chen, Bin Sun, Mengbin Wang, Hao Li, J Fraser Stoddart, Feihe Huang

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
  2. Supramolecular Degraders: An Emerging Paradigm in Targeted Protein Degradation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  3. Article
  4. Article
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  9. Article
  10. Novel macrocycles: from synthesis to supramolecular function.Beilstein journal of organic chemistry · 2026
    Article
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  12. Article
  13. Article
  14. Article
  15. Article
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  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Huangtianzhi Zhu *Stoddart Institute of Molecular Science, Department of Chemistry, Zhejiang University, Hangzhou, P. R. China.ORCID http://orcid.org/0000-0002-1271-6415
Liya Chen *Stoddart Institute of Molecular Science, Department of Chemistry, Zhejiang University, Hangzhou, P. R. China.
Bin SunStoddart Institute of Molecular Science, Department of Chemistry, Zhejiang University, Hangzhou, P. R. China.
Mengbin WangStoddart Institute of Molecular Science, Department of Chemistry, Zhejiang University, Hangzhou, P. R. China.
Hao LiStoddart Institute of Molecular Science, Department of Chemistry, Zhejiang University, Hangzhou, P. R. China. lihao2015@zju.edu.cn.ORCID http://orcid.org/0000-0002-6959-3233
J Fraser StoddartStoddart Institute of Molecular Science, Department of Chemistry, Zhejiang University, Hangzhou, P. R. China. stoddart@northwestern.edu.ORCID http://orcid.org/0000-0003-3161-3697
Feihe HuangStoddart Institute of Molecular Science, Department of Chemistry, Zhejiang University, Hangzhou, P. R. China. fhuang@zju.edu.cn.ORCID http://orcid.org/0000-0003-3177-6744

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Macrocyclic molecules have been used in various fields owing to their guest binding properties. Macrocycle-based host-guest chemistry in solution can allow for precise control of complex formation. Although solution-phase host-guest complexes are easily prepared, their limited stability and processability prevent widespread application. Extending host-guest chemistry from solution to the solid state results in complexes that are generally more robust, enabling easier processing and broadened applications. Macrocyclic compounds in the solid state can encapsulate guests with larger affinities than their soluble counterparts. This is crucial for use in applications such as separation science and devices. In this Review, we summarize recent progress in macrocycle-based solid-state host-guest chemistry and discuss the basic physical chemistry of these complexes. Representative macrocycles and their solid-state complexes are explored, as well as potential applications. Finally, perspectives and challenges are discussed.

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.