Evidence map›Paper›PMID 37783757›Full record

ArticleNature biomedical engineering2023

Synchronized wearables for the detection of haemodynamic states via electrocardiography and multispectral photoplethysmography.

Daniel Franklin, Andreas Tzavelis, Jong Yoon Lee, Ha Uk Chung, Jacob Trueb, Hany Arafa, Sung Soo Kwak, Ivy Huang, Yiming Liu, Megh Rathod and 7 more

Open access · greenAbstract read
In one paragraph

Article in Nature biomedical engineering, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
11.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it, 103 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 2 countries.

Daniel Franklin *Institute of Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada. dan.franklin@utoronto.ca.ORCID 0000-0002-6453-5114
Andreas Tzavelis *Medical Scientist Training Program, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.ORCID 0000-0002-0750-5007
Jong Yoon LeeSibel Health, Niles, IL, USA.
Ha Uk ChungSibel Health, Niles, IL, USA.
Jacob TruebQuerrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL, USA.ORCID 0000-0002-1627-5178
Hany ArafaDepartment of Biomedical Engineering, McCormick School of Engineering, Northwestern University, Evanston, IL, USA.ORCID 0000-0003-3191-8212
Sung Soo KwakQuerrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL, USA.
Ivy HuangQuerrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL, USA.
Yiming LiuDepartment of Electrical and Computer Engineering, McCormick School of Engineering, Northwestern University, Evanston, IL, USA.
Megh RathodInstitute of Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada.
Jonathan WuInstitute of Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada.ORCID 0009-0002-4786-786X
Haolin LiuInstitute of Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada.
Changsheng WuDepartment of Materials Science and Engineering, McCormick School of Engineering, Northwestern University, Evanston, IL, USA.
Jay A PanditScripps Research Translational Institute, San Diego, CA, USA.ORCID 0000-0003-0119-0881
Faraz S AhmadDivision of Cardiology, Department of Medicine, Bluhm Cardiovascular Institute, Northwestern University, Chicago, IL, USA.
Patrick M McCarthyDivision of Cardiac Surgery, Department of Surgery, Bluhm Cardiovascular Institute, Northwestern University, Chicago, IL, USA.
John A RogersDepartment of Biomedical Engineering, McCormick School of Engineering, Northwestern University, Evanston, IL, USA. jrogers@northwestern.edu.ORCID 0000-0002-2980-3961
Northwestern University · USUniversity Health Network · CASibel (United States) · USScripps Research Institute · USUniversity of Toronto · CA

Funding

Scripps Clinical and Translational Science HubUM1TR004407 · NCATS · SCRIPPS RESEARCH INSTITUTE, THE · PI Eric Jeffrey Topol · 2023 to 2026
$24.2M
Skin-like, stretchable, and wearable sensors for monitoring QT interval and hemodynamic variables in Atrial FibrillationF30HL157066 · NHLBI · NORTHWESTERN UNIVERSITY · PI TZAVELIS, ANDREAS · 2021 to 2025
$246k
NCATS NIH HHS UM1 TR004407NHLBI NIH HHS F30 HL157066
6 · The paper itself

Abstract

Cardiovascular health is typically monitored by measuring blood pressure. Here we describe a wireless on-skin system consisting of synchronized sensors for chest electrocardiography and peripheral multispectral photoplethysmography for the continuous monitoring of metrics related to vascular resistance, cardiac output and blood-pressure regulation. We used data from the sensors to train a support-vector-machine model for the classification of haemodynamic states (resulting from exposure to heat or cold, physical exercise, breath holding, performing the Valsalva manoeuvre or from vasopressor administration during post-operative hypotension) that independently affect blood pressure, cardiac output and vascular resistance. The model classified the haemodynamic states on the basis of an unseen subset of sensor data for 10 healthy individuals, 20 patients with hypertension undergoing haemodynamic stimuli and 15 patients recovering from cardiac surgery, with an average precision of 0.878 and an overall area under the receiver operating characteristic curve of 0.958. The multinodal sensor system may provide clinically actionable insights into haemodynamic states for use in the management of cardiovascular disease.

Indexed as

PhotoplethysmographyWearable Electronic DevicesBlood PressureElectrocardiographyHemodynamicsHumans

Identifiers

PMID37783757
PMCPMC10653655
OpenAlexW4387252386

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.