ArticleNature communications2023
NAD
Open access · goldAbstract read
In one paragraph
Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 33 citations in OpenAlex.
- scH16S-Seq Maps Klebsiella pneumoniae-Associated Myeloid States and Reveals a CD38-NAD Immunometabolic Axis That Impairs Lysosomal Acidification in Sepsis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Single nucleotide variant in coenzyme Q6 reprograms macrophage metabolic remodeling in response to inflammatory signals.Research square · 2026Article
- NADFASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026Article
- Molecular strategies ofFrontiers in cellular and infection microbiology · 2026Review
- Article
- Correlation between concentrations of NAMPT and NMNAT1 and the risk of upper respiratory infections in the island reef.World journal of clinical cases · 2025Article
- Integrated multi-omics profiling for risk stratification in Asians with COPD.Respiratory research · 2025Article
- Metabolomic profiling ofmSystems · 2025Article
- Pneumococcal HbioRxiv : the preprint server for biology · 2025Article
- c-di-GMP regulates bacterial NAD biosynthesis via targeting the transcriptional repressor NadR.mBio · 2025Article
- Accelerating Sono-Piezoelectric Charge Transport for Antibacterial Therapy and Bone Regeneration by Metal-Deficient TiOAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- NAD+ metabolism restriction boosts high-dose melphalan efficacy in patients with multiple myeloma.Blood advances · 2025Article
- Baicalin and probenecid protect against Glaesserella parasuis challenge in a piglet model.Veterinary research · 2024Article
- Evolution of fungal tuberculosis necrotizing toxin (TNT) domain-containing enzymes reveals divergent adaptations to enhance NAD cleavage.Protein science : a publication of the Protein Society · 2024Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
23 authors at 10 institutions in 3 countries.
Björn KlabundeInstitute for Lung Research, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Philipps-Universität Marburg, Marburg, Germany.
André WesenerInstitute for Lung Research, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Philipps-Universität Marburg, Marburg, Germany.
Wilhelm BertramsInstitute for Lung Research, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Philipps-Universität Marburg, Marburg, Germany.
Isabell BeinbornInstitute for Lung Research, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Philipps-Universität Marburg, Marburg, Germany.
Nicole PacziaCore Facility for Metabolomics and Small Molecule Mass Spectrometry, Max Planck Institute for Terrestrial Microbiology, Marburg, Germany.
Kristin SurmannDepartment of Functional Genomics, Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany.
Sascha BlankenburgDepartment of Functional Genomics, Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany.
Jochen WilhelmInstitute for Lung Health (ILH), Giessen, Germany.ORCID http://orcid.org/0000-0001-5544-9647
Javier SerraniaCenter for Synthetic Microbiology (SYNMIKRO), Philipps-Universität Marburg, Marburg, Germany.
Kèvin KnoopsMicroscopy CORE Lab, Maastricht Multimodal Molecular Imaging Institute (M4I), Maastricht University, Universiteitssingel 50, 6229 ER, Maastricht, The Netherlands.
Eslam M ElsayedCenter for Synthetic Microbiology (SYNMIKRO), Philipps-Universität Marburg, Marburg, Germany.
Katrin LaakmannInstitute for Lung Research, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Philipps-Universität Marburg, Marburg, Germany.
Anna Lena JungInstitute for Lung Research, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Philipps-Universität Marburg, Marburg, Germany.
Andreas KirschbaumDepartment of Visceral, Thoracic and Vascular Surgery, University Hospital Gießen and Marburg (UKGM), Marburg, Germany.
Sven HammerschmidtDepartment of Molecular Genetics and Infection Biology, Interfaculty Institute for Genetics and Functional Genomics, Center for Functional Genomics of Microbes, University of Greifswald, Greifswald, Germany.ORCID http://orcid.org/0000-0002-6382-6681
Belal AlshaarDivision of Bioanalytical Chemistry, Priority Area Infections, Research Center Borstel, Leibniz Lung Center, Borstel, Germany.
Nicolas GischDivision of Bioanalytical Chemistry, Priority Area Infections, Research Center Borstel, Leibniz Lung Center, Borstel, Germany.ORCID http://orcid.org/0000-0003-3260-5269
Mobarak Abu MraheilInstitute for Medical Microbiology, Justus-Liebig Universität Giessen, Giessen, Germany.
Anke BeckerCenter for Synthetic Microbiology (SYNMIKRO), Philipps-Universität Marburg, Marburg, Germany.ORCID http://orcid.org/0000-0003-4561-9184
Uwe VölkerDepartment of Functional Genomics, Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany.ORCID http://orcid.org/0000-0002-5689-3448
Evelyn VollmeisterInstitute for Lung Research, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Philipps-Universität Marburg, Marburg, Germany.ORCID http://orcid.org/0000-0002-0539-7874
Birke J Benedikter *Institute for Lung Research, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Philipps-Universität Marburg, Marburg, Germany. b.benedikter@maastrichtuniversity.nl.ORCID http://orcid.org/0000-0002-1103-2484
Bernd Schmeck *Institute for Lung Research, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Philipps-Universität Marburg, Marburg, Germany. schmeck@staff.uni-marburg.de.ORCID http://orcid.org/0000-0002-2767-3606
Philipps University of Marburg · DEUniversitätsmedizin Greifswald · DEResearch Center Borstel - Leibniz Lung Center · DEJustus-Liebig-Universität Gießen · DEMaastricht University · NLMaastricht University Medical Centre · NLMax Planck Institute for Terrestrial Microbiology · DEUniversität Greifswald · DEUniversitätsklinikum Gießen und Marburg · DEUniversities of Giessen and Marburg Lung Center · DE
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lower respiratory tract infections caused by Streptococcus pneumoniae (Spn) are a leading cause of death globally. Here we investigate the bronchial epithelial cellular response to Spn infection on a transcriptomic, proteomic and metabolic level. We found the NAD
Indexed as
Bacterial InfectionsNicotinamide-Nucleotide AdenylyltransferaseRespiratory Tract InfectionsAdenosine TriphosphateCell LineCytokinesHumansNADProteomicsAdenosine TriphosphateCytokinesNADNicotinamide-Nucleotide AdenylyltransferaseNMNAT1 protein, human
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.