Evidence map›Paper›PMID 37783579›Full record

ReviewSeminars in perinatology2023

Bronchopulmonary dysplasia - associated pulmonary hypertension: An updated review.

Ahmed El-Saie, Nidhy P Varghese, Melissa K Webb, Natalie Villafranco, Bheru Gandhi, Milenka Cuevas Guaman, Binoy Shivanna

Open access · greenAbstract readReview
In one paragraph

Review in Seminars in perinatology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Role of ROS, soluble guanylate cyclase and cGMP in mouse lung development during hyperoxia.American journal of physiology. Heart and circulatory physiology · 2026
    Article
  4. Review
  5. A hemodynamic-driven approach to chronic pulmonary hypertension in congenital diaphragmatic hernia.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Review
  6. Article
  7. Review
  8. Results of a pulmonary hypertension screening program for premature infants with bronchopulmonary dysplasia.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article
  9. Predicting pulmonary hypertension in infants with bronchopulmonary dysplasia.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article
  10. Article
  11. Pericytes and Lung Vascular Remodeling.Arteriosclerosis, thrombosis, and vascular biology · 2026
    Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Ahmed El-SaieSection of Neonatology, Department of Pediatrics, Children's Mercy Hospital, Kansas City, MO, USA.
Nidhy P VargheseDivision of Pulmonology, Department of Pediatrics, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.
Melissa K WebbDivision of Cardiology, Department of Pediatrics, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.
Natalie VillafrancoDivision of Pulmonology, Department of Pediatrics, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.
Bheru GandhiDivision of Neonatology, Department of Pediatrics, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.
Milenka Cuevas GuamanDivision of Neonatology, Department of Pediatrics, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.
Binoy ShivannaDivision of Neonatology, Department of Pediatrics, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA. Electronic address: shivanna@bcm.edu.
Baylor College of Medicine · USTexas Children's Hospital · USChildren's Mercy Hospital · US

Funding

Mechanistic Roles of Adrenomedullin and its Signaling Receptors in Experimental Bronchopulmonary Dysplasia and Pulmonary HypertensionR01HL139594 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI SHIVANNA, BINOY · 2018 to 2022
$2.0M
Regulatory T cells and Inflammatory Injury of the Developing Murine LungsR03HD103823 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI SHIVANNA, BINOY · 2021 to 2022
$160k
NHLBI NIH HHS R01 HL139594NICHD NIH HHS R03 HD103823
6 · The paper itself

Abstract

Bronchopulmonary dysplasia (BPD) is the leading cause of chronic lung disease in infants and the commonest complication of prematurity. Advances in respiratory and overall neonatal care have increased the survival of extremely low gestational age newborns, leading to the continued high incidence of BPD. Pulmonary hypertension (PH) represents the severe form of the pulmonary vascular disease associated with BPD, and affects almost one-third of infants with moderate to severe BPD. PH responds suboptimally to pulmonary vasodilators and increases morbidity and mortality in BPD infants. An up-to-date knowledge of the pathogenesis, pathophysiology, diagnosis, treatment, and outcomes of BPD-PH can be helpful to develop meaningful and novel strategies to improve the outcomes of infants with this disorder. Therefore, our multidisciplinary team has attempted to thoroughly review and summarize the latest advances in BPD-PH in preventing and managing this morbid lung disorder of preterm infants.

Indexed as

Bronchopulmonary DysplasiaHypertension, PulmonaryGestational AgeHumansInfantInfant, NewbornInfant, PrematureLungBronchopulmonary dysplasiaDiagnosisManagementPathogenesisPulmonary hypertension

Identifiers

PMID37783579
PMCPMC10843293
OpenAlexW4386575239

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.