Evidence map›Paper›PMID 37782797›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Characteristics and anatomic location of PD-1

Se Jin Im, Rebecca C Obeng, Tahseen H Nasti, Daniel McManus, Alice O Kamphorst, Sivaram Gunisetty, Nataliya Prokhnevska, Jennifer W Carlisle, Ke Yu, Gabriel L Sica and 6 more

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed
15.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 65 citations in OpenAlex.

  1. Article
  2. Epigenetic plus cytokine therapy induces stem-like CD8Journal for immunotherapy of cancer · 2026
    Article
  3. Article
  4. Article
  5. Decoding T cell exhaustion in the tumour microenvironment.Experimental & molecular medicine · 2026
    Review
  6. Article
  7. Article
  8. Spatiotemporal dynamics of adoptively transferred stem-like CD8bioRxiv : the preprint server for biology · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. The CD4Nature communications · 2026
    Article
  13. Article
  14. Article
  15. Review
  16. T-Cell Immunity and Lung Cancer.Respirology (Carlton, Vic.) · 2026
    Review
  17. Article
  18. Article
  19. Regulators of CD8Nature reviews. Immunology · 2026
    Review
  20. Review

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 3 countries.

Se Jin Im *Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322.
Rebecca C Obeng *Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322.
Tahseen H NastiEmory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322.ORCID 0000-0002-5650-1563
Daniel McManusEmory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322.
Alice O KamphorstDepartment of Immunology and Immunotherapy, Lipschultz Precision Immunology Institute, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029.ORCID 0000-0002-9230-9501
Sivaram GunisettyEmory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322.
Nataliya ProkhnevskaEmory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322.
Jennifer W CarlisleDepartment of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA 30322.
Ke YuDepartment of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322.
Gabriel L SicaDepartment of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322.
Lucas E CardozoHospital Israelita Albert Eisnstein, Sao Paulo 05652, Brazil.
André N A GonçalvesHospital Israelita Albert Eisnstein, Sao Paulo 05652, Brazil.
Haydn T KissickEmory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322.
Helder I NakayaHospital Israelita Albert Eisnstein, Sao Paulo 05652, Brazil.ORCID 0000-0001-5297-9108
Suresh S RamalingamDepartment of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA 30322.ORCID 0000-0002-0757-3106
Rafi AhmedEmory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322.
Emory University · USHospital Israelita Albert Einstein · BRTisch Hospital · US

Funding

Yerkes National Primate Research Center Role of type-I IFN in regulating COVID-19 induced inflammation and pathogenesisP51OD011132 · OD · EMORY UNIVERSITY · PI Joon Sup Lee · 2012 to 2026
$167.0M
Winship Cancer Institute Cancer Center Support GrantP30CA138292 · NCI · EMORY UNIVERSITY · PI Suresh S Ramalingam · 2009 to 2026
$47.5M
Project 3: Targeting Bax signaling to overcome treatment resistance in NSCLCP50CA217691 · NCI · EMORY UNIVERSITY · PI DENG, XINGMING · 2019 to 2024
$10.1M
Determinants of differentiation and maintenance of PD-1+ CD8 T cellsR01AI153363 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KAMPHORST, ALICE OLIFFSON · 2021 to 2025
$3.3M
NCI NIH HHS P30 CA138292NCI NIH HHS P50 CA217691NIAID NIH HHS R01 AI153363NIH HHS P51 OD011132
6 · The paper itself

Abstract

CD8 T cells play an essential role in antitumor immunity and chronic viral infections. Recent findings have delineated the differentiation pathway of CD8 T cells in accordance with the progenitor-progeny relationship of TCF1

Indexed as

Lung NeoplasmsLymphocytic ChoriomeningitisAnimalsCD8-Positive T-LymphocytesHumansLymphocytic choriomeningitis virusMiceMice, Inbred C57BLPersistent InfectionProgrammed Cell Death 1 ReceptorProgrammed Cell Death 1 Receptorcancer modelschronic viral infectionhuman lung cancerstem-like CD8 T cellstertiary lymphoid structures

Identifiers

PMID37782797
PMCPMC10576122
OpenAlexW4387245750

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.