Evidence map›Paper›PMID 37782691›Full record

ArticleJournal of the American Chemical Society2023

Convergent Total Synthesis of (-)-Cyclopamine.

Manolis Sofiadis, Dongmin Xu, Anthony J Rodriguez, Benedikt Nissl, Sebastian Clementson, Nadia Nasser Petersen, Phil S Baran

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Reconstruction ofEngineering in life sciences · 2026
    Article
  5. Article
  6. Article
  7. Recent advancements in the synthesis ofBeilstein journal of organic chemistry · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Manolis SofiadisDepartment of Chemistry, Scripps Research, 10550 North Torrey Pines Road, La Jolla, California 92037, United States.
Dongmin XuDepartment of Chemistry, Scripps Research, 10550 North Torrey Pines Road, La Jolla, California 92037, United States.
Anthony J RodriguezDepartment of Chemistry, Scripps Research, 10550 North Torrey Pines Road, La Jolla, California 92037, United States.
Benedikt NisslDepartment of Chemistry, Scripps Research, 10550 North Torrey Pines Road, La Jolla, California 92037, United States.
Sebastian ClementsonResearch and Early Development, LEO Pharma A/S, 2750 Ballerup, Denmark.
Nadia Nasser PetersenResearch and Early Development, LEO Pharma A/S, 2750 Ballerup, Denmark.
Phil S BaranDepartment of Chemistry, Scripps Research, 10550 North Torrey Pines Road, La Jolla, California 92037, United States.ORCID 0000-0001-9193-9053

Funding

Scalable Synthesis and New Bond DisconnectionsR35GM118176 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI BARAN, PHIL S · 2016 to 2025
$11.5M
NIGMS NIH HHS R35 GM118176
6 · The paper itself

Abstract

A concise and enantioselective total synthesis of the

Indexed as

AlkenesVeratrum AlkaloidsCyclizationStereoisomerismAlkenescyclopamineVeratrum Alkaloids

Identifiers

PMID37782691
PMCPMC10696607

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.