Evidence map›Paper›PMID 37782524›Full record

ArticleThe American journal of gastroenterology2024

Gastric Alimetry Expands Patient Phenotyping in Gastroduodenal Disorders Compared with Gastric Emptying Scintigraphy.

William Jiaen Wang, Daphne Foong, Stefan Calder, Gabriel Schamberg, Chris Varghese, Jan Tack, William Xu, Charlotte Daker, Daniel Carson, Stephen Waite and 10 more

3 registry-linked trialsOpen access · hybridAbstract read
In one paragraph

Article in The American journal of gastroenterology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
8.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06401746 recruitingnot on this map

Assessment of Gastric Function Using Body Surface Gastric Mapping in Patients on Semaglutide (Ozempic)

TypeobservationalSponsorUniversity of Western SydneyRan2024 to 2025Enrolled15ConditionsSemaglutide-Induced Gastric Motility, GastroparesisArmsGastric Alimetry
NCT06411574 narecruitingnot on this map

Comparing the Impact of Body Surface Gastric Mapping and Gastric Emptying Scintigraphy on Clinical Management in Suspected Gastroparesis

TypeinterventionalSponsorUniversity of Western SydneyRan2024 to 2026Enrolled40ConditionsGastroparesisArmsGastric Alimetry
NCT06854120 recruitingnot on this mapstarted 2025, after this paper: background citation

Body Surface Gastric Mapping in Patients With Dyspeptic Symptoms: Recordings at Baseline and on Medical Therapy

TypeobservationalSponsorUniversity of Auckland, New ZealandRan2025 to 2028Enrolled125ConditionsGastroparesis, Functional DyspepsiaArmsGastric Alimetry
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Gastric slow-wave morphology in health and disease.Digestive diseases and sciences · 2026
    Article
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  19. Gastric AlimetryJournal of clinical medicine · 2023
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors at 8 institutions in 5 countries.

William Jiaen WangSchool of Medicine, Western Sydney University, Campbelltown, Australia.ORCID 0000-0003-4198-1581
Daphne FoongSchool of Medicine, Western Sydney University, Campbelltown, Australia.
Stefan CalderDepartment of Surgery, Auckland City Hospital, Auckland, New Zealand.ORCID 0000-0002-5855-1732
Gabriel SchambergDepartment of Surgery, Auckland City Hospital, Auckland, New Zealand.ORCID 0000-0002-4188-9614
Chris VargheseDepartment of Surgery, Auckland City Hospital, Auckland, New Zealand.ORCID 0000-0001-7369-8639
Jan TackTranslational Research Center for Gastrointestinal Disorders (TARGID), University of Leuven, Leuven, Belgium.ORCID 0000-0002-3206-6704
William XuDepartment of Surgery, Auckland City Hospital, Auckland, New Zealand.
Charlotte DakerDepartment of Gastroenterology, North Shore Hospital, Auckland, New Zealand.ORCID 0000-0001-5218-5973
Daniel CarsonDepartment of Surgery, Auckland City Hospital, Auckland, New Zealand.ORCID 0000-0002-5089-2807
Stephen WaiteAlimetry, Auckland, New Zealand.
Thomas HayesDepartment of Surgery, Auckland City Hospital, Auckland, New Zealand.ORCID 0000-0001-8684-4869
Peng DuAuckland Bioengineering Institute, University of Auckland, Auckland, New Zealand.
Thomas L AbellDivision of Gastroenterology, University of Louisville, Louisville, Kentucky, USA.
Henry P ParkmanGastroenterology Section, Temple University School of Medicine, Philadelphia, Pennsylvania, USA.ORCID 0000-0003-4904-4891
I-Hsuan HuangTranslational Research Center for Gastrointestinal Disorders (TARGID), University of Leuven, Leuven, Belgium.ORCID 0000-0002-9390-6180
Vivian FernandesLumus Imaging Campbelltown and Camden, Sydney, Australia.
Christopher N AndrewsDivision of Gastroenterology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Armen A GharibansDepartment of Surgery, Auckland City Hospital, Auckland, New Zealand.ORCID 0000-0002-9139-4740
Vincent HoSchool of Medicine, Western Sydney University, Campbelltown, Australia.
Greg O'GradyDepartment of Surgery, Auckland City Hospital, Auckland, New Zealand.
Auckland City Hospital · NZCamden and Campbelltown Hospitals · AUUniversity of Auckland · NZKU Leuven · BENorth Shore Hospital · NZTemple University · USUniversity of Calgary · CAUniversity of Louisville · US

Funding

Definitive Evaluation of Gastric Dysrhythmia as a Disease Mechanism by a Novel Body Surface Gastric Mapping TechniqueR56DK126935 · NIDDK · UNIVERSITY OF LOUISVILLE · PI ABELL, THOMAS LYMAN, O'GRADY, GREG · 2021 to 2021
$450k
NIDDK NIH HHS R56 DK126935
6 · The paper itself

Abstract

introductionGastric emptying testing (GET) assesses gastric motility, however, is nonspecific and insensitive for neuromuscular disorders. Gastric Alimetry (GA) is a new medical device combining noninvasive gastric electrophysiological mapping and validated symptom profiling. This study assessed patient-specific phenotyping using GA compared with GET.

methodsPatients with chronic gastroduodenal symptoms underwent simultaneous GET and GA, comprising a 30-minute baseline, 99m TC-labelled egg meal, and 4-hour postprandial recording. Results were referenced to normative ranges. Symptoms were profiled in the validated GA App and phenotyped using rule-based criteria based on their relationships to the meal and gastric activity: (i) sensorimotor, (ii) continuous, and (iii) other.

resultsSeventy-five patients were assessed, 77% female. Motility abnormality detection rates were as follows: GET 22.7% (14 delayed, 3 rapid), GA spectral analysis 33.3% (14 low rhythm stability/low amplitude, 5 high amplitude, and 6 abnormal frequency), and combined yield 42.7%. In patients with normal spectral analysis, GA symptom phenotypes included sensorimotor 17% (where symptoms strongly paired with gastric amplitude, median r = 0.61), continuous 30%, and other 53%. GA phenotypes showed superior correlations with Gastroparesis Cardinal Symptom Index, Patient Assessment of Upper Gastrointestinal Symptom Severity Index, and anxiety scales, whereas Rome IV Criteria did not correlate with psychometric scores ( P > 0.05). Delayed emptying was not predictive of specific GA phenotypes. DISCUSSION: GA improves patient phenotyping in chronic gastroduodenal disorders in the presence and absence of motility abnormalities with increased correlation with symptoms and psychometrics compared with gastric emptying status and Rome IV criteria. These findings have implications for the diagnostic profiling and personalized management of gastroduodenal disorders.

Indexed as

Duodenal DiseasesGastroparesisFemaleGastric EmptyingHumansMaleRadionuclide Imaging

Identifiers

PMID37782524
PMCPMC10872929
OpenAlexW4387241249

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.