Evidence map›Paper›PMID 37782334›Full record

ArticleTAG. Theoretical and applied genetics. Theoretische und angewandte Genetik2023

Molecular characterization of stable QTL and putative candidate genes for grain zinc and iron concentrations in two related wheat populations.

Mengjing Sun, Qiaoling Luo, Qi Zheng, Jingyang Tong, Yue Wang, Jie Song, Yelun Zhang, Zongjun Pu, Jianmin Zheng, Lianzheng Liu and 7 more

Abstract read
PubMed Publisher
In one paragraph

Article in TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
4.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
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  4. Molecular characterization of QTL for grain zinc and iron concentrations in wheat landrace Chinese Spring.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 6 institutions in 3 countries.

Mengjing Sun *Institute of Crop Sciences, Chinese Academy of Agricultural Sciences (CAAS), 12 Zhongguancun South Street, Beijing, 100081, China.
Qiaoling Luo *State Key Laboratory of Plant Cell and Chromosome Engineering, Institute of Genetics and Developmental Biology, The Innovative Academy of Seed Design, Chinese Academy of Sciences, Beijing, 100101, China.
Qi ZhengState Key Laboratory of Plant Cell and Chromosome Engineering, Institute of Genetics and Developmental Biology, The Innovative Academy of Seed Design, Chinese Academy of Sciences, Beijing, 100101, China. qzheng@genetics.ac.cn.
Jingyang TongInstitute of Crop Sciences, Chinese Academy of Agricultural Sciences (CAAS), 12 Zhongguancun South Street, Beijing, 100081, China.
Yue WangInstitute of Crop Sciences, Chinese Academy of Agricultural Sciences (CAAS), 12 Zhongguancun South Street, Beijing, 100081, China.
Jie SongInstitute of Crop Sciences, Chinese Academy of Agricultural Sciences (CAAS), 12 Zhongguancun South Street, Beijing, 100081, China.
Yelun ZhangInstitute of Cereal and Oil Crops, Hebei Academy of Agricultural and Forestry Sciences/Hebei Laboratory of Crop Genetics and Breeding, Shijiazhuang, 050031, Hebei, China.
Zongjun PuInstitute of Crop Sciences, Sichuan Academy of Agricultural Sciences, Chengdu, 610066, Sichuan, China.
Jianmin ZhengInstitute of Crop Sciences, Sichuan Academy of Agricultural Sciences, Chengdu, 610066, Sichuan, China.
Lianzheng LiuInstitute of Grain Crops, Xinjiang Academy of Agricultural Sciences, Urumqi, 830000, Xinjiang, China.
Anding ZhouInstitute of Grain Crops, Xinjiang Academy of Agricultural Sciences, Urumqi, 830000, Xinjiang, China.
Awais RasheedInstitute of Crop Sciences, Chinese Academy of Agricultural Sciences (CAAS), 12 Zhongguancun South Street, Beijing, 100081, China.
Ming LiInstitute of Crop Sciences, Chinese Academy of Agricultural Sciences (CAAS), 12 Zhongguancun South Street, Beijing, 100081, China.
Shuanghe CaoInstitute of Crop Sciences, Chinese Academy of Agricultural Sciences (CAAS), 12 Zhongguancun South Street, Beijing, 100081, China.
Xianchun XiaInstitute of Crop Sciences, Chinese Academy of Agricultural Sciences (CAAS), 12 Zhongguancun South Street, Beijing, 100081, China.
Zhonghu HeInstitute of Crop Sciences, Chinese Academy of Agricultural Sciences (CAAS), 12 Zhongguancun South Street, Beijing, 100081, China.
Yuanfeng HaoInstitute of Crop Sciences, Chinese Academy of Agricultural Sciences (CAAS), 12 Zhongguancun South Street, Beijing, 100081, China. haoyuanfeng@caas.cn.ORCID http://orcid.org/0000-0002-0162-9375
Chinese Academy of Agricultural Sciences · CNChinese Academy of Sciences · CNInstitute of Crop Sciences · CNXinjiang Academy of Agricultural Sciences · CNHebei Academy of Agriculture and Forestry Sciences · CNQuaid-i-Azam University · PK

Funding

Agricultural Science and Technology Innovation Program CAAS-ZDRW202109National Key Research and Development Program of China 2020YFE0202300National Key Research and Development Program of China 2021YFF1000204National Natural Science Foundation of China 31961143007
6 · The paper itself

Abstract

key messageMajor QTL for grain zinc and iron concentrations were identified on the long arm of chromosomes 2D and 6D. Gene-based KASP markers were developed for putative candidate genes TaIPK1-2D and TaNAS10-6D. Micronutrient malnutrition is one of the most common public health problems in the world. Biofortification, the most attractive and sustainable solution to surmount malnutrition requires the development of micronutrient enriched new crop cultivars. In this study, two recombinant inbred line (RIL) populations, ZM175/XY60 and ZM175/LX987, were used to identify QTL for grain zinc concentration (GZnC), grain iron concentration (GFeC) and thousand grain weight (TGW). Eight QTL for GZnC, six QTL for GFeC and five QTL for TGW were detected. Three QTL on chromosomes 2DL and 4BS and chromosome 6A showed pleiotropic effects on all three traits. The 4BS and 6A QTL also increased plant height and might be Rht-B1a and Rht25a, respectively. The 2DL locus within a suppressed recombination region was identified in both RIL populations and the favorable allele simultaneously increasing GZnC, GFeC and TGW was contributed by XY60 and LX987. A QTL on chromosome 6DL associated only with GZnC was detected in ZM175/XY60 and was validated in JD8/AK58 RILs using kompetitive allele-specific PCR (KASP) marker K_AX-110119937. Both the 2DL and 6DL QTL were new loci for GZnC. Based on gene annotations, sequence variations and expression profiles, the phytic acid biosynthesis gene TaIPK1-2D and nicotianamine synthase gene TaNAS10-6D were predicted as candidate genes. Their gene-based KASP markers were developed and validated in a cultivar panel of 343 wheat accessions. This study investigated the genetic basis of GZnC and GFeC and provided valuable candidate genes and markers for breeding Zn- and Fe-enriched wheat.

Indexed as

Genes, PlantIronTriticumZincEdible GrainHumansMalnutritionMicronutrientsPlant BreedingTrace ElementsIronMicronutrientsTrace ElementsZinc

Identifiers

PMID37782334
OpenAlexW4387241776

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.