ArticleEuropean journal of nuclear medicine and molecular imaging2024
Development and performance of SIAT bPET: a high-resolution and high-sensitivity MR-compatible brain PET scanner using dual-ended readout detectors.
Article in European journal of nuclear medicine and molecular imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9 citing papers in PubMed, 19 citations in OpenAlex.
- Performance evaluation of a dedicated brain PET scanner with octagonal detector arrangement using a modified NEMA NU2 2018 protocol.Medical physics · 2026Article
- Initial Performance of a Prototype Small Animal PET Scanner Consisting of Long Semi-Monolithic Scintillator Detectors.Sensors (Basel, Switzerland) · 2026Article
- Performance of high-resolution PET detectors consisting of long GAGG slabs with different reflectors.EJNMMI physics · 2026Article
- Dual-ended readout TOF-DOI PET detectors based on 3.2 mm and 1.6 mm pitch LYSO arrays.EJNMMI physics · 2025Article
- The first human study of add-on PET: A PET-integrated RF coil for 3 T MRI.EJNMMI physics · 2025Article
- A Time-Walk and Timing-Shift Correction Method for Dual-Ended Readout TOF-DOI PET Detectors.IEEE transactions on radiation and plasma medical sciences · 2025Article
- Recent advances in radionuclide medical imaging techniques.Frontiers in medicine · 2025Review
- Performance Characteristics of the NeuroEXPLORER, a Next-Generation Human Brain PET/CT Imager.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2024Article
- PET Detectors Based on Multi-Resolution SiPM Arrays.IEEE transactions on radiation and plasma medical sciences · 2024Article
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20 authors at 1 institution in 1 country.
Funding
Abstract
purposePositron emission tomography/magnetic resonance imaging (PET/MRI) is a powerful tool for brain imaging, but the spatial resolution of the PET scanners currently used for brain imaging can be further improved to enhance the quantitative accuracy of brain PET imaging. The purpose of this study is to develop an MR-compatible brain PET scanner that can simultaneously achieve a uniform high spatial resolution and high sensitivity by using dual-ended readout depth encoding detectors.
methodsThe MR-compatible brain PET scanner, named SIAT bPET, consists of 224 dual-ended readout detectors. Each detector contains a 26 × 26 lutetium yttrium oxyorthosilicate (LYSO) crystal array of 1.4 × 1.4 × 20 mm
resultsA spatial resolution of better than 1.5 mm with an average of 1.2 mm within the whole FOV was obtained. A sensitivity of 11.0% was achieved at the center FOV for an energy window of 350-750 keV. Except for the dedicated RF coil, which caused a ~ 30% reduction of the sensitivity of the PET scanner, the MRI sequences running had a negligible effect on the performance of the PET scanner. The reduction of the SNR and homogeneity of the MRI images was less than 2% as the PET scanner was inserted to the MRI scanner and powered-on. High quality PET and MRI images of a human brain were obtained from simultaneous PET/MRI scans.
conclusionThe SIAT bPET scanner achieved a spatial resolution and sensitivity better than all MR-compatible brain PET scanners developed up to date. It can be used either as a standalone brain PET scanner or a PET insert placed inside a commercial whole-body MRI scanner to perform simultaneous PET/MRI imaging.
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