Evidence map›Paper›PMID 37781651›Full record

ArticleThe journal of allergy and clinical immunology. Global2023

Eosinophil trafficking in allergen-mediated pulmonary inflammation relies on IL-13-driven CCL-11 and CCL-24 production by tissue fibroblasts and myeloid cells.

Pedro H Gazzinelli-Guimaraes, Dominic P Golec, Erik P Karmele, Joshua Sciurba, Pablo Bara-Garcia, Tom Hill, Byunghyun Kang, Sasisekhar Bennuru, Pamela L Schwartzberg, Thomas B Nutman

Open access · goldAbstract read
In one paragraph

Article in The journal of allergy and clinical immunology. Global, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Multi-omics integration andFrontiers in immunology · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. bioRxiv : the preprint server for biology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Pedro H Gazzinelli-GuimaraesLaboratory of Parasitic Diseases, NIAID, National Institutes of Health, Bethesda, MD.
Dominic P GolecLaboratory of Immune System Biology, NIAID, National Institutes of Health, Bethesda, MD.
Erik P KarmeleLaboratory of Molecular Immunology, NIAID, National Institutes of Health, Bethesda, MD.
Joshua SciurbaLaboratory of Parasitic Diseases, NIAID, National Institutes of Health, Bethesda, MD.
Pablo Bara-GarciaLaboratory of Parasitic Diseases, NIAID, National Institutes of Health, Bethesda, MD.
Tom HillNational Institute of Allergy and Infectious Diseases (NIAID) Collaborative Bioinformatics Resource, NIAID, National Institutes of Health, Bethesda, MD.
Byunghyun KangLaboratory of Molecular Immunology, NIAID, National Institutes of Health, Bethesda, MD.
Sasisekhar BennuruLaboratory of Parasitic Diseases, NIAID, National Institutes of Health, Bethesda, MD.
Pamela L SchwartzbergLaboratory of Immune System Biology, NIAID, National Institutes of Health, Bethesda, MD.
Thomas B NutmanLaboratory of Parasitic Diseases, NIAID, National Institutes of Health, Bethesda, MD.
National Institutes of Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The immunologic mechanisms underlying pulmonary type 2 inflammation, including the dynamics of eosinophil recruitment to the lungs, still need to be elucidated. Objective: We sought to investigate how IL-13-producing T Methods: Multiparameter and molecular profiling of murine lungs with HDM-induced allergy was investigated in the absence of IL-13 signaling by using IL-13Rα1-deficient mice and separately through adoptive transfer of CD4 Results: We demonstrated through single-cell techniques that HDM-driven pulmonary inflammation displays a profile characterized by T Conclusion: Our data suggest that IL-5-dependent allergen-specific T

Indexed as

allergyasthmaCCL-11CCL-24eosinophilshelminth parasitesIL-13 signalingTH2 cell responseType 2 inflammation

Identifiers

PMID37781651
PMCPMC10509988
OpenAlexW4382132770

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.