Evidence map›Paper›PMID 37781370›Full record

ArticleFrontiers in immunology2023

Two clip-domain serine protease homologs, cSPH35 and cSPH242, act as a cofactor for prophenoloxidase-1 activation in

Qiao Jin, Yang Wang, Haodong Yin, Haobo Jiang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Partial reconstitution of the prophenoloxidase activation system inProceedings of the National Academy of Sciences of the United States of America · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Qiao JinDepartment of Entomology and Plant Pathology, Oklahoma State University, Stillwater, OK, United States.
Yang WangDepartment of Entomology and Plant Pathology, Oklahoma State University, Stillwater, OK, United States.
Haodong YinDepartment of Entomology and Plant Pathology, Oklahoma State University, Stillwater, OK, United States.
Haobo JiangDepartment of Entomology and Plant Pathology, Oklahoma State University, Stillwater, OK, United States.
Oklahoma State University · US

Funding

Initiation and Regulation of Prophenoloxidase ActivationR01GM058634 · NIGMS · OKLAHOMA STATE UNIVERSITY STILLWATER · PI JIANG, HAOBO · 1999 to 2022
$4.0M
The immune serine protease pathways in Anopheles gambiaeR21AI180325 · NIAID · OKLAHOMA STATE UNIVERSITY STILLWATER · PI JIANG, HAOBO · 2024 to 2025
$409k
Activation and catalytic mechanisms of mosquito phenoloxidasesR21AI139998 · NIAID · OKLAHOMA STATE UNIVERSITY STILLWATER · PI JIANG, HAOBO · 2018 to 2019
$402k
NIAID NIH HHS R21 AI139998NIAID NIH HHS R21 AI180325NIGMS NIH HHS R01 GM058634
6 · The paper itself

Abstract

Insect phenoloxidases (POs) catalyze phenol oxygenation and

Indexed as

Catechol OxidaseDrosophila ProteinsEnzyme PrecursorsSerine ProteasesAnimalsDrosophila melanogasterMelaninsMonophenol MonooxygenaseSerine EndopeptidasesCatechol OxidaseDrosophila ProteinsEnzyme PrecursorsMelaninsMonophenol Monooxygenasepro-phenoloxidaseSerine EndopeptidasesSerine ProteasesSp7 protein, Drosophilaclip domainhemolymph proteininsect immunitymelanizationprotease cascade

Identifiers

PMID37781370
PMCPMC10540698
OpenAlexW4386837004

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.