Evidence map›Paper›PMID 37781339›Full record

ArticleMolecular therapy oncolytics2023

miR-146a inhibits ovarian tumor growth

Rui Chen, Elaina Coleborn, Chintan Bhavsar, Yue Wang, Louisa Alim, Andrew N Wilkinson, Michelle A Tran, Gowri Irgam, Sharat Atluri, Kiefer Wong and 7 more

Open access · goldAbstract read
In one paragraph

Article in Molecular therapy oncolytics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. miR-146a mimic therapy protects against platelet-mediated thrombosis.Molecular therapy : the journal of the American Society of Gene Therapy · 2026
    Article
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  13. CXCL5 impedes CD8Journal of experimental & clinical cancer research : CR · 2024
    Article
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  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 2 countries.

Rui ChenSchool of Biomedical Sciences, The University of Queensland, Brisbane, QLD 4072, Australia.
Elaina ColebornSchool of Biomedical Sciences, The University of Queensland, Brisbane, QLD 4072, Australia.
Chintan BhavsarSchool of Biomedical Sciences, The University of Queensland, Brisbane, QLD 4072, Australia.
Yue WangDepartment of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Louisa AlimSchool of Biomedical Sciences, The University of Queensland, Brisbane, QLD 4072, Australia.
Andrew N WilkinsonSchool of Biomedical Sciences, The University of Queensland, Brisbane, QLD 4072, Australia.
Michelle A TranIcahn School of Medicine, Mount Sinai, New York, NY 10029, USA.
Gowri IrgamSchool of Biomedical Sciences, The University of Queensland, Brisbane, QLD 4072, Australia.
Sharat AtluriSchool of Biomedical Sciences, The University of Queensland, Brisbane, QLD 4072, Australia.
Kiefer WongSchool of Biomedical Sciences, The University of Queensland, Brisbane, QLD 4072, Australia.
Jae-Jun ShimDepartment of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Siddharth AdityanSchool of Biomedical Sciences, The University of Queensland, Brisbane, QLD 4072, Australia.
Ju-Seog LeeDepartment of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Willem W OverwijkDepartment of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Raymond SteptoeFrazer Institute, University of Queensland, Brisbane, QLD 4102, Australia.
Da YangDepartment of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Sherry Y WuSchool of Biomedical Sciences, The University of Queensland, Brisbane, QLD 4072, Australia.
The University of Queensland · AUThe University of Texas MD Anderson Cancer Center · USUniversity of Pittsburgh · USIcahn School of Medicine at Mount Sinai · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunotherapies have emerged as promising strategies for cancer treatment. However, existing immunotherapies have poor activity in high-grade serous ovarian cancer (HGSC) due to the immunosuppressive tumor microenvironment and the associated low tumoral CD8

Indexed as

immunologymicroRNAsnanotherapeuticsovarian cancertumor microenvironment

Identifiers

PMID37781339
PMCPMC10539880
OpenAlexW4386629293

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.