Evidence map›Paper›PMID 37781253›Full record

ArticleFrontiers in neuroscience2023

Interim guidelines for the assessment and treatment of pain in children with multiple sclerosis.

Catherine Stratton, Areti Vassilopoulos, J Nicholas Brenton, Kirsten Potter, Wendy Vargas, Heather Rumm, Andrea Bartels, Mary Bailey, Charles Odonkor, Sharon Stoll and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Pediatric multiple sclerosis: Improving outcome through high-efficacy therapies.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Catherine StrattonDepartment of Epidemiology, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.
Areti VassilopoulosDepartment of Pediatrics, Yale School of Medicine, New Haven, CT, United States.
J Nicholas BrentonDivision of Pediatric Neurology, Department of Neurology, University of Virginia Medical Center, Charlottesville, VA, United States.
Kirsten PotterDepartment of Physical Therapy, Tufts University, Medford, MA, United States.
Wendy VargasDepartment of Neurology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, United States.
Heather RummConnecticut Chapter, National Multiple Sclerosis Society, Hartford, CT, United States.
Andrea BartelsDepartment of Neurology, Yale School of Medicine, New Haven, CT, United States.
Mary BaileyTrinity Health of New England, Hartford, CT, United States.
Charles OdonkorDepartment of Orthopedics and Rehabilitation, Yale School of Medicine, New Haven, CT, United States.
Sharon StollDepartment of Neurology, Yale School of Medicine, New Haven, CT, United States.
E William T ZempskyDivision of Pain & Palliative Medicine, Connecticut Children's Medical Center, Hartford, CT, United States.
E Ann YehDepartment of Paediatrics, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Naila MakhaniDepartment of Pediatrics, Yale School of Medicine, New Haven, CT, United States.

Funding

The Radiologically Isolated Syndrome in ChildrenK23NS101099 · NINDS · YALE UNIVERSITY · PI MAKHANI, NAILA · 2017 to 2022
$792k
NINDS NIH HHS K23 NS101099
6 · The paper itself

Abstract

Introduction: Pain in multiple sclerosis (MS) is common, but literature on pain in children with MS remains scarce. Pain has physical, psychological, and social implications in MS, and both comprehensive assessment and interdisciplinary management approaches are needed. We sought to develop an interdisciplinary interim guideline for the assessment and management of pain in children with MS. Methods and materials: We convened a modified Delphi panel composed of 13 experts in pediatric and adult MS neurology, physiotherapy, pain, patient lived-experience, advanced practice nursing, psychology, physiatry, and MS research. A survey was sent to panelists for anonymous completion. The panel discussed survey themes extracted by the panel chair. The process was repeated twice. Results: Thirteen assessment and treatment recommendations were produced regarding pain in children with MS. Discussion: Future studies will assess implementation of these pain assessment and treatment guidelines in the clinical setting.

Indexed as

clinical guidelineDelphi panelmultiple sclerosispainpediatrics

Identifiers

PMID37781253
PMCPMC10536169

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.