ReviewFrontiers in nutrition2023
Role of micronutrients in the modulation of immune system and platelet activating factor in patients with COVID-19; a narrative review.
Review in Frontiers in nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 19 citations in OpenAlex.
- Impact of Selenium and Vitamin E Deficiency on Zika Virus Pathogenesis and Immune Response in Mice.Viruses · 2026Article
- The immune system as a guardian of health: micronutrient support and lifelong protection.Frontiers in nutrition · 2026Review
- Green Synthesised Carbon Nanodots Using the Maillard Reaction for the Rapid Detection of Elemental Selenium in Water and Carbonated Beverages.Nanomaterials (Basel, Switzerland) · 2025Article
- Reforming Food, Drug, and Nutraceutical Regulations to Improve Public Health and Reduce Healthcare Costs.Foods (Basel, Switzerland) · 2025Review
- A Mixed-Methods Study Exploring the Feasibility of a Digital Combined Lifestyle Intervention for Patients With Post Covid-19 Condition.Health expectations : an international journal of public participation in health care and health policy · 2025Article
- Dietary Antioxidant Index and the Risk of Recurrent Aphthous Stomatitis.International dental journal · 2025Article
- Preoperative malnutrition predicts poor early immune recovery following gynecologic cancer surgery: a retrospective cohort study and risk nomogram development.Frontiers in immunology · 2025Article
- The Role of Vitamins, Magnesium, and Trace Elements in COVID-19 Treatment and Post-COVID-19 Rehabilitation: An Updated Overview.Current medicinal chemistry · 2025Review
- Association between nutritional risk and clinical outcomes in patients with acute exacerbation of chronic obstructive pulmonary disease.American journal of translational research · 2025Article
- Impact of Nutritional Counseling on Knowledge and Lifestyle Related to Immunity Among Academic University Staff in Lima (Peru) During the COVID-19 Pandemic.Risk management and healthcare policy · 2025Article
- Anticancer Potential of Flavonoids: Their Role in Cancer Prevention and Health Benefits.Foods (Basel, Switzerland) · 2024Review
- The effect of a web-based lifestyle intervention on nutritional status and physical activity on prevention of COVID-19: a randomized controlled trial in women's empowerment.Frontiers in nutrition · 2023Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Dietary micronutrients may play important roles in the improvement of the immune responses against SARS-CoV-2. This study aimed to assess the effect of micronutrients on platelet activating factor (PAF) and immunity with a special focus on the coronavirus disease 2019 (COVID-19). Methods: All paper published in English on the effects of micronutrients including fat soluble vitamins, water soluble vitamins, and minerals on PAF, immunity, and COVID-19 were collected from online valid databases. Results: Vitamin A may modulate the expression of PAF-receptor gene in patients with COVID-19. Vitamin D may modulate inflammatory response through influencing PAF pathway. Vitamin E may improve COVID-19 related heart injuries by exert anti-PAF activities. Vitamin C status may have PAF related anti-inflammatory and micro-thrombotic effects in SARS-CoV-2 patients. Furthermore, some trace elements such as copper, selenium, and iron may have key roles in strengthens immunity by inactivate PAF acetyl hydrolase. Conclusion: This narrative review study highlighted the importance of micronutrients in the improvement of immune function through modulation of PAF in patients with COVID-19. Further longitudinal studies are warranted.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.