Evidence map›Paper›PMID 37781008›Full record

ArticleIndian journal of microbiology2023

Dynamics of

Prem Lata Manhas, Megha Sharma, Abhishek Mewara, Man Updesh Sachdeva, Rakesh Sehgal, Pankaj Malhotra

Open access · greenAbstract read
In one paragraph

Article in Indian journal of microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Prem Lata ManhasDepartment of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.ORCID 0000-0001-5103-4110
Megha SharmaDepartment of Medical Parasitology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012 India.
Abhishek MewaraDepartment of Medical Parasitology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012 India.
Man Updesh SachdevaDepartment of Hematology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Rakesh SehgalDepartment of Medical Parasitology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012 India.
Pankaj MalhotraDepartment of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Post Graduate Institute of Medical Education and Research · INAll India Institute of Medical Sciences Raipur · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Malaria in pregnancy causes a dual brunt on the mother as well as the foetus. Upregulation of T-regulatory cells (Tregs) during pregnancy allows tolerance towards the growing foetus, their suppression predisposes the mother to infections. This study analyzed the levels of CD3 Methodology: Total of 114 mice, non-pregnant non-infected (n = 6), non-pregnant infected (n = 12), pregnant non-infected (n = 48) and pregnant infected (n = 48) were included in the study. Infected groups were inoculated intra-peritoneally with 1 × 10 Results: The parasitaemia was significantly higher among early pregnancy infected mice (≥ 70%) than mid-pregnancy infected (40-70%), late pregnancy infected (50-65%), and non-pregnant infected mice (≤ 50%) ( Conclusion: In contrast to non-pregnant mice, the levels of Tregs among pregnant mice decrease when malaria infection is acquired thereby leading to adverse pregnancy outcomes. Supplementary Information: The online version contains supplementary material available at 10.1007/s12088-023-01089-2.

Indexed as

Flow cytometryMalariaP. berghei NK65PregnancyTregs

Identifiers

PMID37781008
PMCPMC10533755
OpenAlexW4386193337

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.