ReviewEXCLI journal2023
Multifunctional role of zinc in human health: an update.
Review in EXCLI journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
49 citing papers in PubMed, 2 syntheses or guidelines pooled it, 72 citations in OpenAlex.
- Effects of Zinc Supplementation on Glycemic Control, Insulin Resistance, Inflammation and Oxidative Stress in Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Endocrinology, diabetes & metabolism · 2026Pooled it
- Assessment of heavy metal contamination in fish, fruits, and vegetables in Southwest Nigeria: A systematic review.F1000Research · 2024Pooled it
- A randomized clinical study to evaluate the possible antifibrotic effect of zinc sulfate in chronic HCV patient receiving direct-acting anti-viral therapy.Inflammopharmacology · 2025Trial
- Zinc-Mediated Modulation of Host-Pathogen Interactions in Poultry: Implications for Salmonella Control and Trace Element Biology.Biological trace element research · 2026Review
- Risk of Zinc Deficiency from Urinary Zinc Loss Induced by Antihypertensive Drugs: A Narrative Review.Biological trace element research · 2026Review
- Zinc-mediated structural and functional regulation of ERp44 and ERGIC-53 in protein quality control.Journal of biochemistry · 2026Review
- Design and Development of Solvent-Sensitive Zn(II)/Al(III) Responsive Chemosensor: Extension to the Real-World Application.ChemPlusChem · 2026Article
- Sex-Specific Prospective Association of Serum Zinc Concentration with Cardiovascular Disease and Mortality: A 10-Year Population-Based Cohort Study.Journal of cardiovascular translational research · 2026Article
- Association of peripheral and CSF zinc levels with Parkinson's disease: A systematic review and meta-analysis.IBRO neuroscience reports · 2026Review
- Biofortifying sunflower with Zinc (Zn) aminochelates: a promising strategy for calcareous soil conditions.BMC plant biology · 2026Article
- Isotopically enrichedScientific reports · 2026Article
- The Impact of Zinc on Cellular Dynamics, Brain Function, and its Therapeutic Potential in Neuronal Regeneration.Molecular neurobiology · 2026Review
- Botulinum Toxin Effects and Its Association with Vitamin and Mineral Supplementation: A Narrative Review.Nutrients · 2026Review
- From Corrosion Control to Cell Adhesion: Parascholzite as a Functional Interface for Biodegradable Zinc Alloys.Materials (Basel, Switzerland) · 2026Article
- Zinc suppresses Stat3-driven IL-6 production in primary mouse adipocytes.Frontiers in immunology · 2026Article
- Elucidating Biological Links in Autism Spectrum Disorder: From Blood-Based Risk Factor Identification to a Validated Nomogram for Early Risk Stratification.Neuropsychiatric disease and treatment · 2026Article
- Serum zinc deficiency and progression of cardiovascular- kidney-metabolic syndrome.Frontiers in nutrition · 2026Article
- Zebrafish as a Model Organism to Study Neurotoxicity: A Potential Tool for Neuroprotective Drug Discovery.Current drug metabolism · 2026Review
- Hidden Hunger in Pediatric Obesity: Redefining Malnutrition Through Macronutrient Quality and Micronutrient Deficiency.Nutrients · 2025Review
- An Exploratory Study of the Nutritional Composition and Caco-2 Safety Assessment of Elche Date Flour and Its Green Hydroethanolic Extracts.Foods (Basel, Switzerland) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Zinc is a multipurpose trace element for the human body, as it plays a crucial part in various physiological processes, such as cell growth and development, metabolism, cognitive, reproductive, and immune system function. Its significance in human health is widely acknowledged, and this has led the scientific community towards more research that aims to uncover all of its beneficial properties, especially when compared to other essential metal ions. One notable area where zinc has shown beneficial effects is in the prevention and treatment of various diseases, including cancer. This review aims to explain the involvement of zinc in specific health conditions such as cancer, coronavirus disease 2019 (COVID-19) and neurological disorders like Alzheimer's disease, as well as its impact on the gut microbiome.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.