Evidence map›Paper›PMID 37780805›Full record

Article3 Biotech2023

Chrysophanol improves memory impairment and cell injury by reducing the level of ferroptosis in A

Jing Luo, Qingyang Lu, Bin Sun, Nan Shao, Wei Huang, Guanhua Hu, Biao Cai, Wenwen Si

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in 3 Biotech, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Jing Luo *College of Integrated Chinese and Western Medicine, Anhui University of Chinese Medicine, Hefei, 230012 China.
Qingyang Lu *College of Integrated Chinese and Western Medicine, Anhui University of Chinese Medicine, Hefei, 230012 China.
Bin Sun *College of Integrated Chinese and Western Medicine, Anhui University of Chinese Medicine, Hefei, 230012 China.
Nan ShaoCollege of Integrated Chinese and Western Medicine, Anhui University of Chinese Medicine, Hefei, 230012 China.
Wei HuangCollege of Integrated Chinese and Western Medicine, Anhui University of Chinese Medicine, Hefei, 230012 China.
Guanhua HuCollege of Integrated Chinese and Western Medicine, Anhui University of Chinese Medicine, Hefei, 230012 China.
Biao CaiCollege of Integrated Chinese and Western Medicine, Anhui University of Chinese Medicine, Hefei, 230012 China.
Wenwen SiCollege of Integrated Chinese and Western Medicine, Anhui University of Chinese Medicine, Hefei, 230012 China.ORCID 0000-0002-7066-9901
Anhui University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) is a common age-related chronic and neurodegenerative disease that has become a global health problem. AD pathogenesis is complex, and the clinical efficacy of commonly used anti-AD drugs is suboptimal. Recent research has revealed a close association between AD-induced damage and the activation of ferroptosis signaling pathways. Chrysophanol (CHR) the principal medicinal component of

Indexed as

Alzheimer’s diseaseChrysophanolFerroptosisGPX4Hippocampus

Identifiers

PMID37780805
PMCPMC10539257
OpenAlexW4387132613

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.