Evidence map›Paper›PMID 37780713›Full record

ArticleFrontiers in neurology2023

Bilateral tonic seizures probably induced by eperisone hydrochloride: a case report.

Long Luo, Jun Yin, Zhigang Li, Wei Zhang, Ying Yuan, Ying Tang, Ye Deng, Ling Zhu

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Eperisone-induced immediate hypersensitivity reactions.The Korean journal of internal medicine · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Long Luo *Department of Neurology, Xiangtan Central Hospital, Xiangtan, Hunan, China.
Jun Yin *Department of Neurology, Xiangya Hospital, Changsha, Hunan, China.
Zhigang LiDepartment of Neurology, Xiangtan Central Hospital, Xiangtan, Hunan, China.
Wei ZhangDepartment of Neurology, Xiangtan Central Hospital, Xiangtan, Hunan, China.
Ying YuanDepartment of Neurology, Xiangtan Central Hospital, Xiangtan, Hunan, China.
Ying TangDepartment of Neurology, Xiangtan Central Hospital, Xiangtan, Hunan, China.
Ye DengDepartment of Neurology, Xiangtan Central Hospital, Xiangtan, Hunan, China.
Ling ZhuDepartment of Neurology, Xiangtan Central Hospital, Xiangtan, Hunan, China.
Xiangyang Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Eperisone hydrochloride is a central muscle relaxant used to treat osteoporosis. Seizures are rare side effects of eperisone hydrochloride and have been previously reported in the medical literature in overdose situations but not at regular doses. This case report describes a 42-year-old male painter who developed severe bilateral tonic seizures after the initiation of eperisone hydrochloride at regular doses for low back pain. Symptoms gradually eased in the days following the discontinuation of eperisone hydrochloride and antiepileptic treatment, with no recurrence. This rare adverse drug reaction warrants clinical awareness; however, the mechanisms underlying these adverse reactions remain to be clarified.

Indexed as

case reportdrugeperisone hydrochloridemuscle relaxantseizurestonic

Identifiers

PMID37780713
PMCPMC10538527
OpenAlexW4386735910

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.