ArticleFrontiers in neurology2023
Association between serum sodium levels within 24 h of admission and all-cause mortality in critically ill patients with non-traumatic subarachnoid hemorrhage: a retrospective analysis of the MIMIC-IV database.
Article in Frontiers in neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 6 citations in OpenAlex.
- Longitudinal Sodium Dynamics After Aneurysmal Subarachnoid Hemorrhage: A Single-Center Cohort Study with a Contemporary Literature Review.Biomedicines · 2026Article
- Machine learning-driven prediction of in-hospital cardiac arrest among critically ill patients with traumatic spinal cord injury: a multicenter cohort study.Frontiers in cardiovascular medicine · 2026Article
- Association between serum sodium trajectories and all-cause mortality in critically ill patients with ischemic stroke: a retrospective analysis of the MIMIC-IV database.European journal of medical research · 2025Article
- Machine learning models for mortality prediction in patients with spontaneous subarachnoid hemorrhage following ICU treatment.Frontiers in neurology · 2025Article
- Hypothermia on the first day of ICU admission leads to increased in-hospital mortality in patients with subarachnoid hemorrhage.Scientific reports · 2024Article
- A prognostic model incorporating the albumin-corrected anion gap in patients with aneurysmal subarachnoid hemorrhage.Frontiers in neurology · 2024Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: The study aimed to evaluate the relationship between serum sodium and mortality in critically ill patients with non-traumatic subarachnoid hemorrhage. Methods: This is a retrospective investigation of critically ill non-traumatic patients with subarachnoid hemorrhage (SAH) utilizing the MIMIC-IV database. We collected the serum sodium levels at admission and determined the all-cause death rates for the ICU and hospital. We employed a multivariate Cox proportional hazard regression model and Kaplan-Meier survival curve analysis to ascertain the relationship between serum sodium and all-cause mortality. In order to evaluate the consistency of correlations, interaction and subgroup analyses were also conducted. Results: A total of 864 patients with non-traumatic SAH were included in this study. All-cause mortality in the ICU and hospital was 32.6% (282/864) and 19.2% (166/864), respectively. Sodium levels at ICU admission showed a statistically significant J-shaped non-linear relationship with ICU and hospital mortality (non-linear Conclusion: High serum sodium levels upon ICU admission are related to higher ICU and hospital all-cause mortality in patients with non-traumatic SAH. A new reference is offered for control strategies to correct serum sodium levels.
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