Evidence map›Paper›PMID 37780486›Full record

ArticleBioMed research international2023

Insampaedok-San Extract Exerts an Immune-Enhancing Effect through NF-

Gyuwon Huh, Youngse Oh, Youngsic Jeon, Ki Sung Kang, Su Nam Kim, Sang Hoon Jung, Seung Hyun Kim, Young-Joo Kim

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Gyuwon HuhNatural Product Research Center, Korea Institute of Science and Technology, Gangneung 25451, Republic of Korea.ORCID https://orcid.org/0009-0005-4760-018X
Youngse OhCollege of Pharmacy, Yonsei Institute of Pharmaceutical Science, Yonsei University, Incheon 21983, Republic of Korea.ORCID https://orcid.org/0000-0001-8985-0578
Youngsic JeonNatural Product Research Center, Korea Institute of Science and Technology, Gangneung 25451, Republic of Korea.ORCID https://orcid.org/0000-0002-5673-5036
Ki Sung KangCollege of Korean Medicine, Gachon University, Seongnam 13120, Republic of Korea.ORCID https://orcid.org/0000-0003-2050-5244
Su Nam KimNatural Product Research Center, Korea Institute of Science and Technology, Gangneung 25451, Republic of Korea.ORCID https://orcid.org/0000-0003-3218-4521
Sang Hoon JungNatural Product Research Center, Korea Institute of Science and Technology, Gangneung 25451, Republic of Korea.
Seung Hyun KimCollege of Pharmacy, Yonsei Institute of Pharmaceutical Science, Yonsei University, Incheon 21983, Republic of Korea.ORCID https://orcid.org/0000-0003-2613-0674
Young-Joo KimNatural Product Research Center, Korea Institute of Science and Technology, Gangneung 25451, Republic of Korea.ORCID https://orcid.org/0000-0003-1080-0581
Yonsei University · KRKorea Institute of Science and Technology · KRBio-Medical Science (South Korea) · KRGachon University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Insampaedok-san (IS) has traditionally been prescribed as a medication for cold-related symptoms in Northeast Asia, including Korea and China. In this study, we focused on elucidating the molecular mechanism underlying the immunomodulatory activity of IS water extract (ISE) in macrophages. ISE significantly enhanced the levels of nitric oxide (NO) and prostaglandin E2 (PGE

Indexed as

Interleukin-6NF-kappa BAnti-Inflammatory AgentsCyclooxygenase 2LipopolysaccharidesNitric OxideNitric Oxide Synthase Type IIRNA, MessengerSignal TransductionAnti-Inflammatory AgentsCyclooxygenase 2Interleukin-6LipopolysaccharidesNF-kappa BNitric OxideNitric Oxide Synthase Type IIRNA, Messenger

Identifiers

PMID37780486
PMCPMC10541303
OpenAlexW4386950288

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.