Evidence map›Paper›PMID 37780360›Full record

ArticleACS central science2023

The Tungsten-Promoted Synthesis of Piperidyl-Modified

Jonathan D Dabbs, Megan N Ericson, Justin H Wilde, Rachel F Lombardo, Earl C Ashcraft, Diane A Dickie, W Dean Harman

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS central science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jonathan D DabbsDepartment of Chemistry, University of Virginia, Charlottesville, Virginia 22904, United States.
Megan N EricsonDepartment of Chemistry, University of Virginia, Charlottesville, Virginia 22904, United States.
Justin H WildeDepartment of Chemistry, University of Virginia, Charlottesville, Virginia 22904, United States.ORCID https://orcid.org/0000-0001-6076-5484
Rachel F LombardoDepartment of Chemistry, University of Virginia, Charlottesville, Virginia 22904, United States.
Earl C AshcraftDepartment of Chemistry, University of Virginia, Charlottesville, Virginia 22904, United States.
Diane A DickieDepartment of Chemistry, University of Virginia, Charlottesville, Virginia 22904, United States.ORCID https://orcid.org/0000-0003-0939-3309
W Dean HarmanDepartment of Chemistry, University of Virginia, Charlottesville, Virginia 22904, United States.ORCID https://orcid.org/0000-0003-0939-6980

Funding

Rapid Synthesis of Topologically Complex Molecules with Tungsten Dearomatization AgentsR01GM132205 · NIGMS · UNIVERSITY OF VIRGINIA · PI HARMAN, WALTER DEAN · 2019 to 2022
$1.3M
NIGMS NIH HHS R01 GM132205
6 · The paper itself

Abstract

Due to its efficacy as a dopamine receptor agonist, methylphenidate (MPH) is of interest as a potential therapeutic for cocaine addiction. While numerous derivatives of MPH have been investigated for their potential medicinal value, functionalization of the piperidine ring has not been explored. The pyridine borane ligand in WTp(NO)(PMe

Identifiers

PMID37780360
PMCPMC10540299

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.