Evidence map›Paper›PMID 37780337›Full record

ArticleFood chemistry: X2023

Analysis for different flavor compounds in mature milk from human and livestock animals by GC × GC-TOFMS.

Yinggang Sun, Yanzhi Wu, Ben Liu, Rui Chen, Yanjun Qiao, Qiu Zhang, Qian Li, Xiaowei Wang, Zeying Wang

Abstract read
In one paragraph

Article in Food chemistry: X, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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  12. Safety evaluation ofFrontiers in microbiology · 2025
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  15. Effects of Fermentation withFoods (Basel, Switzerland) · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yinggang SunCollege of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, China.
Yanzhi WuCollege of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, China.
Ben LiuHuishan Dairy Group, No.111A Huanghe South Street, Huanggu District, Shenyang 110031, China.
Rui ChenCollege of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, China.
Yanjun QiaoCollege of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, China.
Qiu ZhangCollege of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, China.
Qian LiCollege of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, China.
Xiaowei WangCollege of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, China.
Zeying WangCollege of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast milk plays a crucial role in the taste development of infants, which cannot be replicated by other mammalian milk or formulas. This study aimed to identify and characterize the flavor substances in 15 different types of milk and analyze the differences among them. The results showed that human milk contained high levels of esters, particularly fatty acid ethyl esters, which contribute to its unique flavor. The four substances that had the highest flavor contribution in all species were identified as 2,3-butanedione, trimethylamine, isophorone, and acetaldehyde. Furthermore, the analysis of differences revealed that thermal-oxidation of lipids could explain the variation between human milk and other species in terms of flavor compounds. The key differential flavor compounds identified in milk from all species were trimethylamine, propanal, 1-pentanol, pyridine 2-methyl, and 2-butanone. These findings can potentially aid in developing formulas that better meet the taste needs of infants.

Indexed as

Fatty acid ethyl esterFlavoromicRelative odor activity value (ROAV)Thermal oxidationVolatile compounds

Identifiers

PMID37780337
PMCPMC10534127

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.