Evidence map›Paper›PMID 37780205›Full record

ArticleFrontiers in cellular neuroscience2023

Electrophysiological properties of layer 2/3 pyramidal neurons in the primary visual cortex of a retinitis pigmentosa mouse model (

Claas Halfmann, Thomas Rüland, Frank Müller, Kevin Jehasse, Björn M Kampa

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Claas HalfmannSystems Neurophysiology, Institute of Zoology, RWTH Aachen University, Aachen, Germany.
Thomas RülandSystems Neurophysiology, Institute of Zoology, RWTH Aachen University, Aachen, Germany.
Frank MüllerMolecular and Cellular Physiology, Institute of Biological Information Processing (IBI-1), Forschungszentrum Jülich GmbH, Jülich, Germany.
Kevin JehasseSystems Neurophysiology, Institute of Zoology, RWTH Aachen University, Aachen, Germany.
Björn M KampaSystems Neurophysiology, Institute of Zoology, RWTH Aachen University, Aachen, Germany.
RWTH Aachen University · DEForschungszentrum Jülich · DEJülich Aachen Research Alliance · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Retinal degeneration is one of the main causes of visual impairment and blindness. One group of retinal degenerative diseases, leading to the loss of photoreceptors, is collectively termed retinitis pigmentosa. In this group of diseases, the remaining retina is largely spared from initial cell death making retinal ganglion cells an interesting target for vision restoration methods. However, it is unknown how downstream brain areas, in particular the visual cortex, are affected by the progression of blindness. Visual deprivation studies have shown dramatic changes in the electrophysiological properties of visual cortex neurons, but changes on a cellular level in retinitis pigmentosa have not been investigated yet. Therefore, we used the

Indexed as

electrophysiologypatch-clamprd10 mouse modelretinitis pigmentosavisual cortex

Identifiers

PMID37780205
PMCPMC10540630
OpenAlexW4386837625

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.