ArticleThe journal of allergy and clinical immunology. Global2023
Sensitization pattern to environmental allergens in a Japanese population.
Article in The journal of allergy and clinical immunology. Global, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 3 citations in OpenAlex.
- Aeroallergen Sensitization and Its Changes in Adult Asthmatics Managed by Primary Care in the Western Yokohama, Japan.Journal of asthma and allergy · 2026Article
- Sensitization of Common Allergens and Cosensitization Patterns Among Children in Guangzhou, China.Journal of immunology research · 2026Article
- Molecular Signatures of Aeroallergen Sensitization in Pediatric Populations: A Comparative Study Across Spanish Cities.International journal of molecular sciences · 2025Article
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: We previously described the prevalence of allergen-specific IgE in a general population of Japanese adults. Objective: We sought to elucidate allergen sensitization patterns in this population. Methods: Serum samples had been obtained from 800 blood donors aged 20 to 59 years and living in Tokyo, Japan, in 2005 and stored in the Japanese Red Cross Society. These samples were examined for IgE levels, total and specific for 23 allergens or allergen sources correlated with allergic airway diseases using the ImmunoCAP method. Exploratory and confirmatory factor analyses were performed to uncover the relationship among allergen-specific IgE based on their titers. Hierarchical cluster analysis was executed using Ward's method based on standardized factor scores identified through factor analysis. Results: Exploratory factor analysis revealed 6 categories of allergen-specific IgE: specific to 2 types of animals (insects and Conclusions: This study demonstrated that a Japanese population could be divided into 3 clusters according to the sensitization pattern to 6 types of allergens.
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