Evidence map›Paper›PMID 37780057›Full record

ArticleJBMR plus2020

Relationships Among Bone Morphological Parameters and Mechanical Properties of Cadaveric Human Vertebral Cancellous Bone.

Abeer Al-Barghouthi, Seokgi Lee, Giovanni Francesco Solitro, Loren Latta, Francesco Travascio

Open access · goldAbstract read
In one paragraph

Article in JBMR plus, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Abeer Al-BarghouthiDepartment of Orthopaedic Surgery, Max Biedermann Institute for Biomechanics Mount Sinai Medical Center Miami Beach FL USA.
Seokgi LeeDepartment of Industrial Engineering University of Miami Coral Gables FL USA.
Giovanni Francesco SolitroDepartment of Orthopaedic Surgery Louisiana State University Health Science Center-Shreveport Shreveport LO USA.
Loren LattaDepartment of Orthopaedic Surgery, Max Biedermann Institute for Biomechanics Mount Sinai Medical Center Miami Beach FL USA.
Francesco TravascioDepartment of Orthopaedic Surgery, Max Biedermann Institute for Biomechanics Mount Sinai Medical Center Miami Beach FL USA.ORCID https://orcid.org/0000-0002-9301-9266
University of Miami · USLouisiana State University in Shreveport · USMount Sinai Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mechanical properties and morphological features of the vertebral cancellous bone are related to resistance to fracture and capability of withstanding surgical treatments. In particular, vertebral strength is related to its elastic properties, whereas the ease of fluid motion, related to the success of incorporation orthopedic materials (eg, bone cement), is regulated by the hydraulic permeability (K). It has been shown that both elastic modulus and permeability of a material are affected by its morphology. The objective of this study was to establish relations between local values of K and the aggregate modulus (H), and parameters descriptive of the bone morphology. We hypothesized that multivariate statistical models, by including the contribution of several morphology parameters at once, would provide a strong correlation with K and H of the vertebral cancellous bone. Hence, μCT scans of human lumbar vertebra were used to determine a set of bone morphology descriptors. Subsequently, indentation tests on the bone samples were conducted to determine local values of K and H. Finally, a multivariate approach supported by principal component analysis was adopted to develop predictive statistical models of bone permeability and aggregate modulus as a function of bone morphology descriptors. It was found that linear combinations of bone volume fraction, trabecular thickness, trabecular spacing, structure model index, connectivity density, and degree of anisotropy provide a strong correlation (

Indexed as

AGGREGATE MODULUSBONE VOLUME FRACTIONHYDRAULIC PERMEABILITYMECHANICAL INDENTATIONμCT

Identifiers

PMID37780057
PMCPMC10540741
OpenAlexW3006115655

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.