ArticleDigital journal of ophthalmology : DJO2023
Delayed presentation of surgically induced scleral necrosis after I-BRITE procedure treated with immunosuppressive therapy.
Article in Digital journal of ophthalmology : DJO, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed, 1 citations in OpenAlex.
- Global Perspectives on Therapy for Noninfectious Conjunctival Hyperemia: A Narrative Review.Ophthalmology and therapy · 2026Review
- High-Dose-Rate Yttrium-90 (Ophthalmology scienceArticle
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Authors and funding
8 authors at 3 institutions in 2 countries.
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Abstract
Surgically induced scleral necrosis (SISN) is an uncommon complication of ocular procedures. Cosmetic eye-whitening surgery involves conjunctival and Tenon's capsule dissection, cautery, and mitomycin C application. We report the case of a 36-year-old white woman referred to our clinic for severe pain, scleral inflammation, and necrosis in both eyes 9 years after I-BRITE, an elective eye-whitening procedure. An extensive workup yielded negative results. The patient improved with aggressive lubrication and topical and high-dose systemic prednisone (60 mg), with recurrence upon steroid tapering. Concomitant weekly methotrexate was added, resulting in inflammatory control and allowing discontinuance of topical and oral steroids.
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