Evidence map›Paper›PMID 37779827›Full record

ArticleCurrent health sciences journal

Preliminary Study on the Antioxidant Effect of Natural Based Products with Potential Application in Complex Regional Pain Syndrome.

Cristina-Elena Biță, Ștefan Cristian Dinescu, Florentin Ananu Vreju, Anca Emanuela Mușetescu, Andrei Biță, Cristina Criveanu, Andreea Lili Bărbulescu, Alesandra Florescu, Paulina Lucia Ciurea

Open access · greenAbstract read
In one paragraph

Article in Current health sciences journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 74% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Cristina-Elena BițăDepartment of Rheumatology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, Romania.
Ștefan Cristian DinescuDepartment of Rheumatology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, Romania.
Florentin Ananu VrejuDepartment of Rheumatology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, Romania.
Anca Emanuela MușetescuDepartment of Rheumatology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, Romania.
Andrei BițăDepartment of Pharmacognosy, Faculty of Pharmacy, University of Medicine and Pharmacy of Craiova, Romania.
Cristina CriveanuDepartment of Rheumatology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, Romania.
Andreea Lili BărbulescuDepartment of Pharmacology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, Romania.
Alesandra FlorescuDepartment of Rheumatology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, Romania.
Paulina Lucia CiureaDepartment of Rheumatology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, Romania.
University of Medicine and Pharmacy of Craiova · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Complex regional pain syndrome (CRPS) is a complex condition characterized by chronic pain and various sensory, motor, and autonomic symptoms. It involves a complex interplay of mechanisms in the nervous system, including neuroinflammation, sensitization of pain pathways, and dysfunction of the sympathetic nervous system. Antioxidants may play a role in CRPS by helping to counteract oxidative stress, which is an imbalance between the production of reactive oxygen species (ROS) and the body's antioxidant defences. CRPS involves inflammation and tissue damage, which can lead to increased ROS production and oxidative stress. Our paper represents a preliminary study on various commercially available natural-based products regarding their antioxidant effect. Several natural products with antioxidant properties, such as vitamins C and E, polyphenols, flavonoids, and botanical extracts, have shown promise in preclinical studies for their potential to alleviate pain and reduce inflammation associated with CRPS. The potential use of natural-based products with antioxidant effects for mitigating CRPS symptoms is still an area of ongoing research and investigation, but nonetheless it holds promise.

Indexed as

antioxidantCRPSDPPHnatural products

Identifiers

PMID37779827
PMCPMC10541066
OpenAlexW4387241771

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.