Evidence map›Paper›PMID 37779581›Full record

ArticleToxicological research2023

Effects of grape seed proanthocyanidin extract on side effects of high-dose methylprednisolone administration in male rats.

Aslihan Sur, Seda Iflazoglu Mutlu, Pinar Tatli Seven, Ismail Seven, Abdullah Aslan, Meltem Kizil, Recai Kulaksiz, Mustafa Hilmi Yaranoglu, Selim Esen

Open access · greenAbstract read
In one paragraph

Article in Toxicological research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Aslihan SurDepartment of Veterinary Medicine, Vocational School of Kepsut, Balikesir University, 10000 Balikesir, Turkey.
Seda Iflazoglu MutluDepartment of Animal Nutrition and Nutritional Diseases, Faculty of Veterinary Medicine, Firat University, 23119 Elazig, Turkey.
Pinar Tatli SevenDepartment of Animal Nutrition and Nutritional Diseases, Faculty of Veterinary Medicine, Firat University, 23119 Elazig, Turkey.
Ismail SevenDepartment of Plant and Animal Production, Vocational School of Sivrice, Firat University, 23119 Elazig, Turkey.
Abdullah AslanDepartment of Biology, Faculty of Science, Firat University, 23119 Elazig, Turkey.
Meltem KizilDepartment of Physiology, Faculty of Veterinary Medicine, Firat University, 23119 Elazig, Turkey.
Recai KulaksizDepartment of Reproduction and Artificial Insemination, Faculty of Veterinary Medicine, Balikesir University, 10000 Balikesir, Turkey.
Mustafa Hilmi YaranogluExperimental Research Center, Balikesir University, 10000 Balikesir, Turkey.
Selim EsenBalikesir Directorate of Provincial Agriculture and Forestry, Republic of Turkey Ministry of Agriculture and Forestry, 10470 Balikesir, Turkey.ORCID 0000-0001-9270-7086
Fırat University · TRBalıkesir University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we investigated the effects of grape seed proanthocyanidin extract (GSPE) against the side effects of high-dose administration of methylprednisolone (MP) in male rats. A total of 32 adult Wistar male albino rats were divided into four groups: (1) control (CON), received standard food only; (2) MP, received standard food + intraperitoneal injection of 60 mg/kg MP on day 7; (3) GSPE, received standard food + 200 mg/kg/day GSPE; and (4) MP + GSPE, received standard food + 200 mg/kg/day of GSPE + intraperitoneal injection of 60 mg/kg MP on day 7. All animals in the GSPE and GSPE + MP groups were treated once a day by oral gavage for 14 consecutive days. The feed intake of rats in the MP and MP + GSPE groups decreased significantly by 24.14% and 13.52%, respectively (

Indexed as

ApoptosisBiomarkerGrape seed proanthocyanidin extractMethylprednisoloneSperm characteristic

Identifiers

PMID37779581
PMCPMC10541365
OpenAlexW4383550421

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.