Evidence map›Paper›PMID 37779528›Full record

ArticleThe journal of allergy and clinical immunology. Global2023

Reduced toxicity conditioning and a high CD34

Ambreen Pandrowala, Ajay Narayan Sharma, Manasa Kakunje, Minnie Bodhanwala, Prashant Hiwarkar

Open access · goldAbstract read
In one paragraph

Article in The journal of allergy and clinical immunology. Global, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Ambreen PandrowalaDepartment of Blood and Marrow Transplantation, Mumbai, India.
Ajay Narayan SharmaDepartment of Blood and Marrow Transplantation, Mumbai, India.
Manasa KakunjeDepartment of Blood and Marrow Transplantation, Mumbai, India.
Minnie BodhanwalaDepartment of Pediatrics, Bai Jerbai Wadia Hospital for Children, Mumbai, India.
Prashant HiwarkarDepartment of Blood and Marrow Transplantation, Mumbai, India.
European Society for Blood and Marrow Transplantation · NLBai Jerbai Wadia Hospital for Children · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Biallelic mutations in the dedicator of cytokinesis 8 ( Objective: Here we have sought to devise a strategy for reducing the possibility of mixed chimerism without increasing the risk of transplant-related mortality. Methods: To balance the risk of transplant-related mortality and mixed chimerism, we used treosulfan-based reduced toxicity conditioning with a high CD34 Results: We are able to report that by using the aforementioned novel strategy, we achieved excellent transplant outcomes in the first cohort of high-risk patients with DOCK8 deficiency from India. Conclusion: High CD34

Indexed as

bone marrow transplantationchimerismDOCK8 deficiencyHSCT

Identifiers

PMID37779528
PMCPMC10510004
OpenAlexW4361199122

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.