Evidence map›Paper›PMID 37779512›Full record

ArticleTransplant international : official journal of the European Society for Organ Transplantation2023

Liver Inclusion Appears to Be Protective Against Graft Loss-Due-to Chronic But Not Acute Rejection Following Intestinal Transplantation.

Rodrigo Vianna, Jeffrey J Gaynor, Gennaro Selvaggi, Ahmed Farag, Jennifer Garcia, Akin Tekin, Marina M Tabbara, Gaetano Ciancio

Open access · goldAbstract read
In one paragraph

Article in Transplant international : official journal of the European Society for Organ Transplantation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 2 countries.

Rodrigo ViannaDepartment of Surgery, Miami Transplant Institute, Miller School of Medicine, University of Miami, Miami, FL, United States.
Jeffrey J GaynorDepartment of Surgery, Miami Transplant Institute, Miller School of Medicine, University of Miami, Miami, FL, United States.
Gennaro SelvaggiDepartment of Surgery, Miami Transplant Institute, Miller School of Medicine, University of Miami, Miami, FL, United States.
Ahmed FaragDepartment of Surgery, Miami Transplant Institute, Miller School of Medicine, University of Miami, Miami, FL, United States.
Jennifer GarciaDepartment of Pediatrics, Miami Transplant Institute, Miller School of Medicine, University of Miami, Miami, FL, United States.
Akin TekinDepartment of Surgery, Miami Transplant Institute, Miller School of Medicine, University of Miami, Miami, FL, United States.
Marina M TabbaraDepartment of Surgery, Miami Transplant Institute, Miller School of Medicine, University of Miami, Miami, FL, United States.
Gaetano CiancioDepartment of Surgery, Miami Transplant Institute, Miller School of Medicine, University of Miami, Miami, FL, United States.
Miami Transplant Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In intestinal transplantation, while other centers have shown that liver-including allografts have significantly more favorable graft survival and graft loss-due-to chronic rejection (CHR) rates, our center has consistently shown that modified multivisceral (MMV) and full multivisceral (MV) allografts have significantly more favorable acute cellular rejection (ACR) and severe ACR rates compared with isolated intestine (I) and liver-intestine (LI) allografts. In the attempt to resolve this apparent discrepancy, we performed stepwise Cox multivariable analyses of the hazard rates of developing graft loss-due-to acute rejection (AR) vs. CHR among 350 consecutive intestinal transplants at our center with long-term follow-up (median: 13.5 years post-transplant). Observed percentages developing graft loss-due-to AR and CHR were 14.3% (50/350) and 6.6% (23/350), respectively. Only one baseline variable was selected into the Cox model indicating a significantly lower hazard rate of developing graft loss-due-to AR: Transplant Type MMV or MV (

Indexed as

Liver TransplantationGraft RejectionGraft SurvivalHumansIntestinesLiverLiving DonorsTransplantation, Homologouschronic rejectiongraft loss-due-to acute rejectiongraft loss-due-to chronic rejectionintestinal transplantationlong-term results CHRprognostic factors

Identifiers

PMID37779512
PMCPMC10538304
OpenAlexW4386743022

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.