Evidence map›Paper›PMID 37779205›Full record

ArticleBMC public health2023

Exposures to humidifier disinfectant and various health conditions in Korean based on personal exposure assessment data of claimants for compensation.

Myeongjin Hong, Min Jae Ju, Jeonggyo Yoon, Wonyoung Lee, Seula Lee, Eun-Kyung Jo, Seo-Youn Choi, Wonho Yang, Yoon-Hyeong Choi

Open access · goldAbstract read
In one paragraph

Article in BMC public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Myeongjin Hong *Department of Preventive Medicine, Gachon University College of Medicine, Incheon, Korea.
Min Jae Ju *Department of Preventive Medicine, Gachon University College of Medicine, Incheon, Korea.
Jeonggyo YoonDepartment of Community, Environment and Policy, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ, USA.
Wonyoung LeeDepartment of Preventive Medicine, Gachon University College of Medicine, Incheon, Korea.
Seula LeeDepartment of Preventive Medicine, Gachon University College of Medicine, Incheon, Korea.
Eun-Kyung JoKorean Society of Environmental Health, Seoul, Korea.
Seo-Youn ChoiDepartment of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Wonho YangDepartment of Occupational Health, Daegu Catholic University, Gyeongbuk, Korea.
Yoon-Hyeong ChoiSchool of Health and Environmental Science, College of Health Science, Korea University, 145 Anam-Ro, Seongbuk-Gu, 02841, Seoul, Republic of Korea. yoonchoi@korea.ac.kr.
Gachon University · KRCatholic University of Daegu · KRKorea University · KRSungkyunkwan University · KRUniversity of Arizona · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHumidifier disinfectants (HDs) were commonly used household chemicals to prevent microbial growth in a humidifier water tank in South Korea. A growing body of evidence has indicated that its airborne exposure can induce severe lung injury. However, there has been low awareness of other health outcomes in HD users. This study aimed to evaluate health conditions appealed by claimants for compensation in relation with an increased exposure to HD.

methodsFrom survey data of personal HD exposure assessment of claimants for compensation in Korea, we included a total of 4,179 subjects [cases in each dataset were defined by nine reported health conditions, i.e., pneumonia, asthma, cardiovascular disease, respiratory disease, otorhinolaryngologic disease, brain disease (including cerebrovascular disease), dermatological disease, lung cancer, and all cancers]. HD exposures was considered as the following exposure criteria: exposure duration, exposure proximity, exposure direction, chemical type, cumulative exposure time, indoor air concentration, and cumulative exposure level. Logistic regression models were used to evaluate the associations between HD exposure and health conditions.

resultsAfter adjusting for sociodemographic and health behavioral factors and other chemical exposures (households, environmental, and occupational exposures), an increase in cumulative HD exposure time was significantly associated with risks of all nine diseases (all p-trends < 0.05). An increase in HD exposure duration was associated with asthma, respiratory disease, otorhinolaryngologic disease, dermatological disease, all cancers, and lung cancer (p-trends < 0.05). Indoor HD concentration was associated with only pneumonia (p-trend = 0.015).

conclusionsOur findings suggest that cumulative exposures to airborne HD might potentially increase the risk of various reported health outcomes.

Indexed as

AsthmaDisinfectantsLung NeoplasmsOtorhinolaryngologic DiseasesPneumoniaHumansHumidifiersRepublic of KoreaDisinfectantsHumidifier disinfectantHumidifier disinfectant exposureReported health conditions

Identifiers

PMID37779205
PMCPMC10544189
OpenAlexW4387234615

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.