Evidence map›Paper›PMID 37779204›Full record

ArticleChinese medicine2023

Thermal treatment enhances the resisting exercise fatigue effect of Phyllanthus emblica L.: novel evidence from tannin conversion in vitro, metabolomics, and gut microbiota community analysis.

Dingkun Zhang, Xuan Deng, Mengqi Li, Min Qiu, Yifan Zhang, Gefei Li, Yurou Jiang, Peng Tan, Sanhu Fan, Youde Zheng and 3 more

Open access · goldAbstract read
In one paragraph

Article in Chinese medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Dingkun Zhang *State Key Laboratory of Southwestern Chinese Medicine Resources, Pharmacy College, Chengdu University of TCM, Chengdu, 611137, China.
Xuan Deng *State Key Laboratory of Southwestern Chinese Medicine Resources, Pharmacy College, Chengdu University of TCM, Chengdu, 611137, China.ORCID http://orcid.org/0000-0001-7528-9847
Mengqi LiPharmacy Department, Sichuan Nursing Vocational College, Chengdu, 610100, China.
Min QiuState Key Laboratory of Southwestern Chinese Medicine Resources, Pharmacy College, Chengdu University of TCM, Chengdu, 611137, China.
Yifan ZhangState Key Laboratory of Southwestern Chinese Medicine Resources, Pharmacy College, Chengdu University of TCM, Chengdu, 611137, China.
Gefei LiState Key Laboratory of Southwestern Chinese Medicine Resources, Pharmacy College, Chengdu University of TCM, Chengdu, 611137, China.
Yurou JiangState Key Laboratory of Southwestern Chinese Medicine Resources, Pharmacy College, Chengdu University of TCM, Chengdu, 611137, China.
Peng TanState Key Laboratory of Quality Evaluation of Traditional Chinese Medicine, Sichuan Academy of Traditional Chinese Medicine, Chengdu, 610041, China.
Sanhu FanSanajon Pharmaceutical Group, Chengdu, 610000, China.
Youde ZhengSanajon Pharmaceutical Group, Chengdu, 610000, China.
Junzhi LinTCM Regulating Metabolic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610072, People's Republic of China. 582097013@qq.com.
Li HanState Key Laboratory of Southwestern Chinese Medicine Resources, Pharmacy College, Chengdu University of TCM, Chengdu, 611137, China. hanliyx@163.com.
Haozhou HuangState Key Laboratory of Southwestern Chinese Medicine Resources, Innovative Institute of Chinese Medicine and Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China. 1539889839@qq.com.
Chengdu University of Traditional Chinese Medicine · CNChengdu Medical College · CNSichuan Academy of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polyphenols are the main component of Phyllanthus emblica (PE). However, polyphenols are so easy to transform that it is unknown that how drying methods driven by heating affect the anti-fatigue effect of PE. This manuscript investigated the effects of five drying methods on the chemical composition transformation and anti-fatigue of PE, and discussed the action mechanism. The results suggested that the anti-fatigue effect of PE with hot-air-dried at 100 °C was the best, which was as 1.63 times as that with freeze-drying. Ellagic acid (EA) may be a key component of PE in anti-fatigue, and its mechanism of action may be related to regulating intestinal microbiota, protecting mitochondria, and regulating energy metabolism. This study first revealed the thermal transformation of polyphenols in PE, found the most effective strategy for enhancing the anti-fatigue function, and explores its action mechanism.

Indexed as

Drying methodEllagic acidGallic acidPhyllanthus emblica L.Resisting exercise fatigue effect

Identifiers

PMID37779204
PMCPMC10544184
OpenAlexW4387232976

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.