ArticleScientific reports2023
Evaluation of an automated dish preparation system for IVF and embryo culture using a mouse mode.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed.
- Automation, Artificial Intelligence (AI), and Digital Management in IVF Laboratories: Current Status, Challenges and Potential.Reproductive sciences (Thousand Oaks, Calif.) · 2026Review
- Prioritizing embryologist health: occupational health hazards and preventive strategies.Frontiers in public health · 2026Review
- Safety and efficacy of the automated liquid-phase embryo storage, Hatchferti: a pilot study.PeerJ · 2026Article
- Automation in vitrification and thawing of mouse oocytes and embryos.Frontiers in cell and developmental biology · 2023Article
- Embryologist staffing in assisted reproductive technology laboratories: An international comparative review.Reproductive medicine and biologyReview
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Manual dish preparation for IVF in human fertility clinics or animal laboratories heavily relies on embryologists' experience, which can lead to occupational illness due to long-term and monotonous operation. Therefore, introducing an automated technique to replace traditional methods is crucial for improving working efficiency and reducing work burden for embryologists. In the current study in the mouse, both manual and automated methods were used to prepare IVF or embryo culture dishes. A one-way analysis of variance was conducted to compare several factors, including preparation time, qualified rates, media osmolality of dishes, fertilization rates, and embryonic development to assess the efficiency and potential of automated preparation. The results showed that automation system significantly reduced the required time and increased the efficiencies and qualified rates of dish preparation, especially for embryo culture dishes, without significantly altering medium osmolalities. There were no significant differences between two preparations in fertilization rates and embryo development in mice. Thus, automated dish preparation can improve working efficiency and qualified rates while maintaining fertilization rates and subsequent embryonic development without compromising osmolality stability of medium. It presents a superior alternative to manual preparation, reducing the workload of embryologists and facilitating the standardization of operational procedures.
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Registered trials
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