Evidence map›Paper›PMID 37779135›Full record

SynthesisNeurosurgical review2023

Outcomes following surgical and endovascular treatment of extracranial vertebral artery aneurysms (VAA): a systematic evaluation of the literature.

Oluwatoyin Akinnusotu, Atiq Ur Rehman Bhatti, Abdul Karim Ghaith, Antonio Bon Nieves, Ryan Jarrah, Waseem Wahood, Mohamad Bydon, Bernard R Bendok

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Neurosurgical review, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Oluwatoyin AkinnusotuMeharry Medical College, Nashville, TN, USA.
Atiq Ur Rehman BhattiNeuro-Informatics Laboratory, Mayo Clinic College of Medicine and Science, Rochester, MN, USA.
Abdul Karim GhaithNeuro-Informatics Laboratory, Mayo Clinic College of Medicine and Science, Rochester, MN, USA.
Antonio Bon NievesNeuro-Informatics Laboratory, Mayo Clinic College of Medicine and Science, Rochester, MN, USA.
Ryan JarrahNeuro-Informatics Laboratory, Mayo Clinic College of Medicine and Science, Rochester, MN, USA.
Waseem WahoodNova Southeastern University Dr. Kiran C. Patel College of Allopathic Medicine, Davie, FL, 33328, USA.
Mohamad BydonNeuro-Informatics Laboratory, Mayo Clinic College of Medicine and Science, Rochester, MN, USA. bydon.mohamad@mayo.edu.
Bernard R BendokDepartment of Neurological Surgery, Mayo Clinic, Phoenix, AZ, USA.
Mayo Clinic · USNeurological Surgery · USMayo Clinic Hospital · USMayo Clinic in Arizona · USMeharry Medical College · USNova Southeastern University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extracranial vertebral artery aneurysms are rare complications resulting from trauma and multiple different diseases. However, the difference between clinical and surgical profiles is well understood. To investigate the clinical and interventional outcomes following extracranial vertebral artery aneurysms (VAA) treatment through a systematic review of the literature to date, an electronic database search for full-text English articles was conducted following PRISMA guidelines. The search yielded results on clinical and surgical outcomes for extracranial VAAs. These results included patient-specific risk factors, indications, and techniques. Our literature search resulted in 561 articles, of which 36 studies were qualified to be included in the analysis. A total of 55 patients with multiple various extracranial VAA incidents were included. The mean age of subjects was 42 years (ranging from 13.0 to 76.0 years), and the majority of patients were males (71%, n =39). Blunt trauma was the most frequent risk factor for extracranial VAA formation (35%, n = 19). The majority of aneurysms (60%) were dissected in nature. The most common form of treatment for extracranial VAAs was the use of a flow diverter (24%, n=13). Overall, five (9%) patients had long-term adverse neurological complications following intervention with 5% (n=3) mortality, 2% (n=1) resulting in unilateral vocal cord paralysis, and 2% (n=1) resulted in a positive Romberg sign. The mortality rate is 15.7% in the surgical group, whereas the endovascular treatment did not result in any mortality. The endovascular approach is a safe and effective treatment of extracranial VAAs due to its relatively low overall complication rate and lack of resulting mortality. This is in contrast to the surgical approach which results in a higher rate of complications, recurrence, and mortality outcomes. An understanding of the factors and clinical outcomes associated with the incidence of extracranial VAAs is essential for the future improvement of patient outcomes.

Indexed as

AneurysmEndovascular ProceduresAdultFemaleHumansMaleRetrospective StudiesTreatment OutcomeVertebral ArteryBlunt traumaExtracranial vertebral artery aneurysmsIschemic strokes

Identifiers

PMID37779135
OpenAlexW4387242192

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.