Evidence map›Paper›PMID 37779067›Full record

ArticleInternal medicine (Tokyo, Japan)2024

STAT1 Mutations in Chronic Mucocutaneous Candidiasis Diagnosed in an Adult.

Miya Andou, Masaki Tominaga, Ryuta Nishikomori, Kenji Gotoh, Nobukazu Komatsu, Masanobu Matsuoka, Tomotaka Kawayama, Tomoaki Hoshino

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Miya AndouDivision of Respirology, Neurology and Rheumatology, Department of Medicine, Kurume University School of Medicine, Japan.
Masaki TominagaDepartment of Community Medicine, Kurume University School of Medicine, Japan.
Ryuta NishikomoriDepartment of Pediatrics and Child Health, Kurume University School of Medicine, Japan.
Kenji GotohDepartment of Infection Control and Prevention, Kurume University School of Medicine, Japan.
Nobukazu KomatsuDepartment of Immunology, Kurume University School of Medicine, Japan.
Masanobu MatsuokaDivision of Respirology, Neurology and Rheumatology, Department of Medicine, Kurume University School of Medicine, Japan.
Tomotaka KawayamaDivision of Respirology, Neurology and Rheumatology, Department of Medicine, Kurume University School of Medicine, Japan.
Tomoaki HoshinoDivision of Respirology, Neurology and Rheumatology, Department of Medicine, Kurume University School of Medicine, Japan.
Kurume University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 30-year-old man presented with oral candidiasis and a history of lung abscess. He experienced recurring oral and skin candidiasis in childhood but spent long periods without any infections. Therefore, immunodeficiency was suspected. T and B lymphocyte and natural killer cell counts as well as immunoglobulin levels were normal. Human immunodeficiency virus test results were negative. Therefore, we suspected chronic mucocutaneous candidiasis (CMC). The signal transducer and activator of transcription (STAT) mutation, the leading cause of CMC, was detected by exome sequencing. Most cases of STAT1 mutations are diagnosed in childhood, but a few are diagnosed in adulthood because Candida infections may not be severe.

Indexed as

Candidiasis, Chronic MucocutaneousMutationSTAT1 Transcription FactorAdultExome SequencingHumansMaleSTAT1 protein, humanSTAT1 Transcription Factorchronic mucocutaneous candidiasissignal transducer and activator of transcription 1 (STAT1)STAT-1-GOFtarget exome sequencing

Identifiers

PMID37779067
PMCPMC11116016
OpenAlexW4387123556

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.