Evidence map›Paper›PMID 37778459›Full record

ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2024

Belatacept with time-limited tacrolimus coimmunosuppression modifies the 3-year risk of eplet mismatch in kidney transplantation.

Aileen C Johnson, Joan Zhang, Geeta Karadkhele, Loren Gragert, Vicki Hertzberg, Christian P Larsen

Open access · bronzeAbstract read
In one paragraph

Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. De novo belatacept-based immunosuppression is not associated with increased risk of invasive fungal infection in kidney transplant recipients.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2026
    Article
  2. Article
  3. Abatacept as maintenance therapy in kidney transplantation: a retrospective comparative study.Transplant international : official journal of the European Society for Organ Transplantation · 2026
    Article
  4. Review
  5. Optimizing kidney allocation: challenges and solutions.Current opinion in organ transplantation · 2025
    Review
  6. Review
  7. Immunosuppression Management in Heart Transplantation.Methodist DeBakey cardiovascular journal · 2025
    Review
  8. Belatacept in Kidney Transplantation: Reflecting on the Past, Shaping the Future.Transplant international : official journal of the European Society for Organ Transplantation · 2025
    Review
  9. HLA-DR/DQ eplet mismatch predictsFrontiers in genetics · 2024
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Aileen C JohnsonDepartment of Surgery, Emory University School of Medicine, Atlanta, Georgia, USA.
Joan ZhangDepartment of Surgery, Emory University School of Medicine, Atlanta, Georgia, USA.
Geeta KaradkheleDepartment of Surgery, Emory University School of Medicine, Atlanta, Georgia, USA.
Loren GragertDepartment of Pathology, Tulane University School of Medicine, New Orleans, Louisiana, USA.
Vicki HertzbergWoodruff School of Nursing, Emory University, Atlanta, Georgia, USA.
Christian P LarsenDepartment of Surgery, Emory University School of Medicine, Atlanta, Georgia, USA. Electronic address: clarsen@emory.edu.
Emory University · USTulane University · US

Funding

Selective CD28 Blockade in Renal Transplant RecipientsU01AI138909 · NIAID · EMORY UNIVERSITY · PI BADELL, IDELBERTO RAUL, FORD, MANDY L · 2018 to 2022
$4.9M
Advanced Research Training in Transplantation ScienceT32AI070081 · NIAID · EMORY UNIVERSITY · PI Mandy L Ford · 2006 to 2026
$3.1M
NIAID NIH HHS T32 AI070081NIAID NIH HHS U01 AI138909
6 · The paper itself

Abstract

Solid organ transplant donor-recipient eplet mismatch has been correlated with donor-specific antibody (DSA) formation, antibody-mediated rejection, and overall rejection rates. However, studies have been predominantly in patients on tacrolimus-based immunosuppression regimens and have not fully explored differences in ethnically and racially diverse populations. Evidence indicates that patients on belatacept have lower rates of DSA formation, suggesting mediation of the immunogenicity of mismatched human leukocyte antigen polymorphisms. We performed a retrospective, single-center analysis of class II eplet disparity in a cohort of kidney transplant recipients treated using belatacept with tacrolimus induction (Bela/Tac

Indexed as

Kidney TransplantationTacrolimusAbataceptAntibodiesGraft RejectionGraft SurvivalHistocompatibility TestingHumansRetrospective StudiesAbataceptAntibodiesTacrolimusantibodybelataceptcostimulationepletHLAimmunosuppressionrejection

Identifiers

PMID37778459
PMCPMC10842047
OpenAlexW4387165531

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.