Evidence map›Paper›PMID 37778410›Full record

ArticleThe Journal of pediatrics2024

Blood Pressure Outcomes in NICU-Admitted Infants with Neonatal Hypertension: A Pediatric Nephrology Research Consortium Study.

Nianzhou Xiao, Michelle Starr, Adrienne Stolfi, Gilad Hamdani, Shireen Hashmat, Stefan G Kiessling, Christina Sethna, Mahmoud Kallash, Robyn Matloff, Robert Woroniecki and 7 more

Registry-linked trialOpen access · greenAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07547917 (Improving the Measurement of Neonatal High Blood Pressure Using the Boppli Device), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07547917 naenrolling by invitationnot on this mapstarted 2026, after this paper: background citation

Improving the Measurement of Neonatal High Blood Pressure Using the Boppli Device

TypeinterventionalSponsorIndiana UniversityRan2026 to 2031Enrolled30ConditionsHypertension, NeonatalArmsBoppli
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 17 institutions in 3 countries.

Nianzhou XiaoDepartment of Nephrology, Valley Children's Healthcare, Madera, CA. Electronic address: nxiao@valleychildrens.org.
Michelle StarrRiley Hospital for Children and Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN; Division of Nephrology, Department of Pediatrics, University of Washington and Seattle Children's Hospital, Seattle, WA.
Adrienne StolfiDepartment of Pediatrics, Wright State University, Dayton, OH.
Gilad HamdaniNephrology and Hypertension Institute, Schneider's Children Medical Center, Petah Tikva, Israel.
Shireen HashmatDepartment of Pediatrics, University of Chicago, Chicago, IL.
Stefan G KiesslingDivision of Pediatric Nephrology, Kentucky Children's Hospital, University of Kentucky, Lexington, KY.
Christina SethnaDivision of Pediatric Nephrology, Cohen Children's Medical Center, Zucker School of Medicine at Hofstra/Northwell, Queens, NY.
Mahmoud KallashDivision of Nephrology, Nationwide Children's Hospital, Columbus, OH.
Robyn MatloffDivision of Pediatric Nephrology, Connecticut Children's Hospital, University of Connecticut School of Medicine, Hartford, CT.
Robert WoronieckiDivision of Pediatric Nephrology and Hypertension, Renaissance School of Medicine at Stony Brook University, Stony Brook, NY.
Keia SandersonDivision of Nephrology and Hypertension, University of North Carolina, Chapel Hill, NC.
Ikuyo YamaguchiDivision of Nephrology and Hypertension, Department of Pediatrics, Oklahoma Children's Hospital at University of Oklahoma Health Sciences Center, Oklahoma, OK.
Stephen D ChaDivision of Nephrology, Akron Children's Hospital, Akron, OH.
Michael G SemanikDivision of Nephrology, Department of Pediatrics, University of Wisconsin at Madison, Madison, WI.
Rahul ChanchlaniDivision of Pediatric Nephrology, Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada.
Joseph T FlynnDivision of Nephrology, Department of Pediatrics, University of Washington and Seattle Children's Hospital, Seattle, WA.
Mark MitsnefesDivision of Nephrology and Hypertension, Cincinnati Children's Medical Center, Cincinnati, OH.
Akron Children's Hospital · USChildren's Hospital Central California · USChildren's Hospital of Oklahoma · USCincinnati Children's Hospital Medical Center · USCohen Children's Medical Center · USConnecticut Children's Medical Center · USIndiana University – Purdue University Indianapolis · USMcMaster University · CANationwide Children's Hospital · USSchneider Children's Medical Center · ILStony Brook University · USUniversity of Chicago · USUniversity of Kentucky · USUniversity of North Carolina at Chapel Hill · USUniversity of Washington · USUniversity of Wisconsin–Madison · USWright State University · US

Funding

Pediatric Nephrology Training ProgramT32DK007662 · NIDDK · UNIVERSITY OF WASHINGTON · PI HINGORANI, SANGEETA · 1991 to 2020
$5.5M
CTSA K12 Program at Indiana UniversityK12TR004415 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI SAMIR KUMAR GUPTA · 2023 to 2026
$3.4M
Machine Learning Risk Prediction of Kidney Disease After Extremely Preterm BirthK23DK131289 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SANDERSON, KEIA · 2023 to 2025
$602k
NCATS NIH HHS K12 TR004415NIDDK NIH HHS K23 DK131289NIDDK NIH HHS L40 DK130155NIDDK NIH HHS T32 DK007662
6 · The paper itself

Abstract

objectiveTo describe the blood pressure outcomes of infants admitted to the neonatal intensive care unit (NICU) with idiopathic (nonsecondary) hypertension (HTN) who were discharged on antihypertensive therapy. STUDY

designRetrospective, multicenter study of 14 centers within the Pediatric Nephrology Research Consortium. We included all infants with a diagnosis of idiopathic HTN discharged from the NICU on antihypertensive treatment. The primary outcome was time to discontinuation of antihypertensive therapy, grouped into (≤6 months, >6 months to 1 year, and >1 year). Comparisons between groups were made with χ

resultsData from 118 infants (66% male) were included. Calcium channel blockers were the most prescribed class of antihypertensives (56%) in the cohort. The percentages remaining on antihypertensives after NICU discharge were 60% at 6 months, 26% at 1 year, and 7% at 2 years. Antenatal steroid treatment was associated with decreased likelihood of antihypertensive therapy >1 year after discharge.

conclusionsThis multicenter study reports that most infants admitted to the NICU diagnosed with idiopathic HTN will discontinue antihypertensive treatment by 2 years after NICU discharge. These data provide important insights into the outcome of neonatal HTN, but should be confirmed prospectively.

Indexed as

HypertensionInfant, Newborn, DiseasesNephrologyAntihypertensive AgentsBlood PressureChildFemaleHumansInfantInfant, NewbornIntensive Care Units, NeonatalMalePregnancyRetrospective StudiesAntihypertensive AgentshypertensionneonatesNICUpediatric

Identifiers

PMID37778410
PMCPMC10980536
OpenAlexW4387190422

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.