Evidence map›Paper›PMID 37778387›Full record

ArticlePhilosophical transactions of the Royal Society of London. Series B, Biological sciences2023

Transcriptomic analysis of PADI4 target genes during multi-lineage differentiation of embryonic stem cells.

Anup Kumar Singh, Soumen Khan, Daniel Moore, Simon Andrews, Maria A Christophorou

Open access · hybridAbstract read
In one paragraph

Article in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Citrullination: new tricks for an old mod.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Article
  4. Transcriptomic analysis of PADI4 target genes during multi-lineage differentiation of embryonic stem cells.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Anup Kumar SinghEpigenetics, Babraham Institute, Cambridge CB22 3AT, UK.
Soumen KhanEpigenetics, Babraham Institute, Cambridge CB22 3AT, UK.
Daniel MooreEpigenetics, Babraham Institute, Cambridge CB22 3AT, UK.
Simon AndrewsBioinformatics Facility, Babraham Institute, Cambridge CB22 3AT, UK.
Maria A ChristophorouEpigenetics, Babraham Institute, Cambridge CB22 3AT, UK.ORCID 0000-0001-5455-7283
Babraham Institute · GB

Funding

Biotechnology and Biological Sciences Research Council BBS/E/B/000C0421Wellcome TrustWellcome Trust 105642/Z/14/Z
6 · The paper itself

Abstract

During mammalian embryo development, pluripotent epiblast cells diversify into the three primary germ layers, which will later give rise to all fetal and adult tissues. These processes involve profound transcriptional and epigenetic changes that require precise coordination. Peptidylarginine deiminase IV (PADI4) is a transcriptional regulator that is strongly associated with inflammation and carcinogenesis but whose physiological roles are less well understood. We previously found that

Indexed as

Endothelial CellsProtein-Arginine Deiminase Type 4TranscriptomeAnimalsCell DifferentiationEmbryonic Stem CellsMiceProtein-Arginine DeiminasesPadi4 protein, mouseProtein-Arginine DeiminasesProtein-Arginine Deiminase Type 4embryonic stem cellslineage specificationpeptidylarginine deiminase

Identifiers

PMID37778387
PMCPMC10542446
OpenAlexW4387231955

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.