Evidence map›Paper›PMID 37777558›Full record

ArticleScientific reports2023

Genetic contributions to brain serotonin transporter levels in healthy adults.

Silvia Elisabetta Portis Bruzzone, Arafat Nasser, Sagar Sanjay Aripaka, Marie Spies, Brice Ozenne, Peter Steen Jensen, Gitte Moos Knudsen, Vibe Gedsoe Frokjaer, Patrick MacDonald Fisher

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Silvia Elisabetta Portis BruzzoneNeurobiology Research Unit, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.
Arafat NasserNeurobiology Research Unit, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.
Sagar Sanjay AripakaNeurobiology Research Unit, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.
Marie SpiesDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
Brice OzenneNeurobiology Research Unit, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.
Peter Steen JensenNeurobiology Research Unit, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.
Gitte Moos KnudsenNeurobiology Research Unit, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.
Vibe Gedsoe FrokjaerNeurobiology Research Unit, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.
Patrick MacDonald FisherNeurobiology Research Unit, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark. patrick.fisher@nru.dk.
University of Copenhagen · DKCopenhagen University Hospital · DKMedical University of Vienna · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The serotonin transporter (5-HTT) critically shapes serotonin neurotransmission by regulating extracellular brain serotonin levels; it remains unclear to what extent 5-HTT levels in the human brain are genetically determined. Here we applied [

Indexed as

NeocortexSerotonin Plasma Membrane Transport ProteinsAdultBrainHumansMesencephalonPositron-Emission TomographySerotoninTomography, X-Ray ComputedSerotoninSerotonin Plasma Membrane Transport ProteinsSLC6A4 protein, human

Identifiers

PMID37777558
PMCPMC10542378
OpenAlexW4387218654

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.