ArticleNature communications2023
Multi-heme cytochrome-mediated extracellular electron transfer by the anaerobic methanotroph 'Candidatus Methanoperedens nitroreducens'.
Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 52 citations in OpenAlex.
- Biophotocatalytic and bioelectrocatalytic strategies for methane production and oxidation: emerging pathways and perspectives.Archives of microbiology · 2026Review
- Microbiome and plasmidome shifts drive carbon, nitrogen, and greenhouse gas dynamics within transitioning permafrost.Environmental microbiome · 2026Article
- Methanoperedenaceae archaea: a 20-year research journey.Nature communications · 2026Review
- Mechanisms of Direct Electron Transfer Governed by Redox-Active Conductive Carrier with Superior Wettability in Anaerobic Biofilms.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Viral communities from long-term anaerobic alkane-oxidizing enrichment cultures encode predicted cell surface adhesion functions.The ISME journal · 2026Article
- Redox conduction facilitates direct interspecies electron transport in anaerobic methanotrophic consortia.Science advances · 2025Article
- Methanotrophic Flexibility of 'Ca. Methanoperedens' and Its Interactions With Sulphate-Reducing Bacteria in the Sediment of Meromictic Lake Cadagno.Environmental microbiology · 2025Article
- Microbial magnetite oxidation via MtoAB porin-multiheme cytochrome complex inApplied and environmental microbiology · 2025Article
- Cometabolism of ferrihydrite reduction and methyl-dismutating methanogenesis byApplied and environmental microbiology · 2025Article
- Microbial magnetite oxidation via MtoAB porin-multiheme cytochrome complex inbioRxiv : the preprint server for biology · 2025Article
- Humin oxidation drives microbial dehalogenation in oligotrophic environments.The ISME journal · 2025Article
- Back flux during anaerobic oxidation of butane support archaea-mediated alkanogenesis.Nature communications · 2024Article
- Diversity, Methane Oxidation Activity, and Metabolic Potential of Microbial Communities in Terrestrial Mud Volcanos of the Taman Peninsula.Microorganisms · 2024Article
- Mechanisms of extracellular electron transfer in anaerobic methanotrophic archaea.Nature communications · 2024Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Anaerobic methanotrophic archaea (ANME) carry out anaerobic oxidation of methane, thus playing a crucial role in the methane cycle. Previous genomic evidence indicates that multi-heme c-type cytochromes (MHCs) may facilitate the extracellular electron transfer (EET) from ANME to different electron sinks. Here, we provide experimental evidence supporting cytochrome-mediated EET for the reduction of metals and electrodes by 'Candidatus Methanoperedens nitroreducens', an ANME acclimated to nitrate reduction. Ferrous iron-targeted fluorescent assays, metatranscriptomics, and single-cell imaging suggest that 'Ca. M. nitroreducens' uses surface-localized redox-active cytochromes for metal reduction. Electrochemical and Raman spectroscopic analyses also support the involvement of c-type cytochrome-mediated EET for electrode reduction. Furthermore, several genes encoding menaquinone cytochrome type-c oxidoreductases and extracellular MHCs are differentially expressed when different electron acceptors are used.
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