Evidence map›Paper›PMID 37777515›Full record

ArticleNature communications2023

PET-measured human dopamine synthesis capacity and receptor availability predict trading rewards and time-costs during foraging.

Angela M Ianni, Daniel P Eisenberg, Erie D Boorman, Sara M Constantino, Catherine E Hegarty, Michael D Gregory, Joseph C Masdeu, Philip D Kohn, Timothy E Behrens, Karen F Berman

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Brain-Behavior Relationships: Neural Mechanisms of Impulsivity and Compulsivity in Neuropsychiatric Disorders.Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology · 2025
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Angela M IanniClinical & Translational Neuroscience Branch, National Institutes of Mental Health, Intramural Research Program, National Institutes of Health, Bethesda, MD, USA. ianniam@upmc.edu.ORCID http://orcid.org/0000-0003-3512-6896
Daniel P EisenbergClinical & Translational Neuroscience Branch, National Institutes of Mental Health, Intramural Research Program, National Institutes of Health, Bethesda, MD, USA.ORCID http://orcid.org/0000-0003-4306-9342
Erie D BoormanWellcome Centre for Integrative Neuroimaging, University of Oxford, Oxford, United Kingdom.
Sara M ConstantinoDepartment of Psychology, New York University, New York, NY, USA.ORCID http://orcid.org/0000-0001-5533-5885
Catherine E HegartyClinical & Translational Neuroscience Branch, National Institutes of Mental Health, Intramural Research Program, National Institutes of Health, Bethesda, MD, USA.
Michael D GregoryClinical & Translational Neuroscience Branch, National Institutes of Mental Health, Intramural Research Program, National Institutes of Health, Bethesda, MD, USA.ORCID http://orcid.org/0000-0003-3749-8343
Joseph C MasdeuClinical & Translational Neuroscience Branch, National Institutes of Mental Health, Intramural Research Program, National Institutes of Health, Bethesda, MD, USA.ORCID http://orcid.org/0000-0001-9955-6954
Philip D KohnClinical & Translational Neuroscience Branch, National Institutes of Mental Health, Intramural Research Program, National Institutes of Health, Bethesda, MD, USA.
Timothy E Behrens *Wellcome Centre for Integrative Neuroimaging, University of Oxford, Oxford, United Kingdom.ORCID http://orcid.org/0000-0003-0048-1177
Karen F Berman *Clinical & Translational Neuroscience Branch, National Institutes of Mental Health, Intramural Research Program, National Institutes of Health, Bethesda, MD, USA.
National Institutes of Health · USUniversity of Oxford · GBHouston Methodist · USNortheastern University · US

Funding

Neuroimaging of Brain Circuits and Neurogenetic Mechanisms in Normal CognitionZIAMH002717 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI BERMAN, KAREN FAITH · 2009 to 2024
$21.8M
Intramural NIH HHS ZIA MH002717
6 · The paper itself

Abstract

Foraging behavior requires weighing costs of time to decide when to leave one reward patch to search for another. Computational and animal studies suggest that striatal dopamine is key to this process; however, the specific role of dopamine in foraging behavior in humans is not well characterized. We use positron emission tomography (PET) imaging to directly measure dopamine synthesis capacity and D

Indexed as

DopamineReceptors, Dopamine D2AdultAnimalsCorpus StriatumHumansPositron-Emission TomographyRewardDopamineReceptors, Dopamine D2

Identifiers

PMID37777515
PMCPMC10542376
OpenAlexW4387222541

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.