Evidence map›Paper›PMID 37777508›Full record

ArticleNature communications2023

Heat-inactivated Bifidobacterium adolescentis ameliorates colon senescence through Paneth-like-cell-mediated stem cell activation.

Yadong Qi, Jiamin He, Yawen Zhang, Qiwei Ge, Qiwen Wang, Luyi Chen, Jilei Xu, Lan Wang, Xueqin Chen, Dingjiacheng Jia and 7 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
11.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  6. Review
  7. Review
  8. Article
  9. Journal of microbiology and biotechnology · 2026
    Article
  10. A multifunctional probiotic co-delivery platform for the treatment of Clostridium difficile infection.Journal of controlled release : official journal of the Controlled Release Society · 2026
    Article
  11. Article
  12. Article
  13. Review
  14. Gut microbes · 2025
    Article
  15. Article
  16. Review
  17. Article
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 2 institutions in 1 country.

Yadong Qi *Department of Gastroenterology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Jiamin He *Department of Gastroenterology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Yawen Zhang *Department of Gastroenterology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Qiwei Ge *Institute of Gastroenterology, Zhejiang University, Hangzhou, Zhejiang, China.ORCID http://orcid.org/0000-0003-1689-6836
Qiwen Wang *Department of Gastroenterology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Luyi ChenPrevention and Treatment Research Center for Senescent Disease, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.ORCID http://orcid.org/0000-0002-5023-5858
Jilei XuDepartment of Gastroenterology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Lan WangDepartment of Gastroenterology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Xueqin ChenDepartment of Gastroenterology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Dingjiacheng JiaInstitute of Gastroenterology, Zhejiang University, Hangzhou, Zhejiang, China.ORCID http://orcid.org/0000-0002-0089-4580
Yifeng LinInstitute of Gastroenterology, Zhejiang University, Hangzhou, Zhejiang, China.
Chaochao XuInstitute of Gastroenterology, Zhejiang University, Hangzhou, Zhejiang, China.
Ying ZhangInstitute of Gastroenterology, Zhejiang University, Hangzhou, Zhejiang, China.
Tongyao HouDepartment of Gastroenterology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Jianmin SiDepartment of Gastroenterology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China. sijm@zju.edu.cn.ORCID http://orcid.org/0000-0001-6257-2512
Shujie ChenDepartment of Gastroenterology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China. chenshujie77@zju.edu.cn.ORCID http://orcid.org/0000-0001-5099-5569
Liangjing WangInstitute of Gastroenterology, Zhejiang University, Hangzhou, Zhejiang, China. wangljzju@zju.edu.cn.ORCID http://orcid.org/0000-0001-8227-8855
Sir Run Run Shaw Hospital · CNSecond Affiliated Hospital of Zhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Declined numbers and weakened functions of intestinal stem cells (ISCs) impair the integrity of the intestinal epithelium during aging. However, the impact of intestinal microbiota on ISCs in this process is unclear. Here, using premature aging mice (telomerase RNA component knockout, Terc

Indexed as

Bifidobacterium adolescentisAnimalsColonHot TemperatureIntestinal MucosaIntestinesMiceStem Cells

Identifiers

PMID37777508
PMCPMC10542354
OpenAlexW4387215538

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.