Evidence map›Paper›PMID 37777287›Full record

ArticleThe Lancet. Public health2023

All-cause hospitalisation among people living with HIV according to gender, mode of HIV acquisition, ethnicity, and geographical origin in Europe and North America: findings from the ART-CC cohort collaboration.

Sophia M Rein, Fiona C Lampe, Suzanne M Ingle, Jonathan A C Sterne, Adam Trickey, M John Gill, Vasileios Papastamopoulos, Linda Wittkop, Marc van der Valk, Maria Kitchen and 7 more

Abstract read
In one paragraph

Article in The Lancet. Public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Sophia M ReinCAUSALab and Department of Epidemiology, Harvard T H Chan School of Public Health, Harvard University, Boston, MA, USA; Institute for Global Health, UCL, London, UK. Electronic address: srein@hsph.harvard.edu.
Fiona C LampeInstitute for Global Health, UCL, London, UK.
Suzanne M InglePopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Jonathan A C SternePopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK; NIHR Bristol Biomedical Research Centre, Bristol, UK; Health Data Research UK South-West, Bristol, UK.
Adam TrickeyPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
M John GillDepartment of Medicine, University of Calgary, Calgary, AB, Canada.
Vasileios PapastamopoulosDepartment of Internal Medicine and Infectious Diseases, Evaggelismos General Hospital, Athens, Greece.
Linda WittkopUniversity of Bordeaux, INSERM, Bordeaux Population Health-U1219, CIC1401-EC, Bordeaux, France; CHU de Bordeaux-Bordeaux University Hospital, Service d'information médicale, INSERM, CIC-EC 1401, Bordeaux, Franc; SISTM, INRIA, University of Bordeaux, Talence, France.
Marc van der ValkDepartment of Infectious Diseases, Amsterdam Infection and Immunity Institute (AI&II), Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands; Stichting HIV Monitoring, Amsterdam, Netherlands.
Maria KitchenDepartment of Dermatology, Venereology, and Allergology, Medical University of Innsbruck, Innsbruck, Austria.
Jodie L GuestDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Derek D SatreDepartment of Psychiatry and Behavioral Sciences, University of California, San Francisco, CA, USA; Division of Research, Kaiser Permanente Northern California, Oakland, CA, USA.
Gilles WandelerDepartment of Infectious Diseases, Bern University Hospital, University of Bern, Switzerland.
Pepa GalindoHospital Clínico Universitario de Valencia, Valencia, Spain.
Jessica CastilhoDivision of Infectious Diseases, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Heidi M CraneDepartment of Medicine and Department of Health Services, University of Washington, Seattle, WA, USA.
Colette J SmithInstitute for Global Health, UCL, London, UK.

Funding

2/3 COMpAAAS Tripartite: ART-CC, KP, and VAU01AA026230 · NIAAA · KAISER FOUNDATION RESEARCH INSTITUTE · PI SATRE, DEREK D, SILVERBERG, MICHAEL J · 2017 to 2021
$3.0M
1/3 Collaborative Research in HIV/AIDS, Alcohol, and Related Comorbidities (COMpAAAS) Tripartite: ART-CC, KP, and VAU01AA026209 · NIAAA · UNIVERSITY OF BRISTOL · PI STERNE, JONATHAN · 2017 to 2021
$2.2M
Improving Alcohol and Drug Services for Older AdultsK23AA015411 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SATRE, DEREK D · 2005 to 2009
$684k
NIAAA NIH HHS K23 AA015411NIAAA NIH HHS U01 AA026209NIAAA NIH HHS U01 AA026230
6 · The paper itself

Abstract

backgroundUnderstanding demographic disparities in hospitalisation is crucial for the identification of vulnerable populations, interventions, and resource planning.

methodsData were from the Antiretroviral Therapy Cohort Collaboration (ART-CC) on people living with HIV in Europe and North America, followed up between January, 2007 and December, 2020. We investigated differences in all-cause hospitalisation according to gender and mode of HIV acquisition, ethnicity, and combined geographical origin and ethnicity, in people living with HIV on modern combination antiretroviral therapy (cART). Analyses were performed separately for European and North American cohorts. Hospitalisation rates were assessed using negative binomial multilevel regression, adjusted for age, time since cART intitiaion, and calendar year.

findingsAmong 23 594 people living with HIV in Europe and 9612 in North America, hospitalisation rates per 100 person-years were 16·2 (95% CI 16·0-16·4) and 13·1 (12·8-13·5). Compared with gay, bisexual, and other men who have sex with men, rates were higher for heterosexual men and women, and much higher for men and women who acquired HIV through injection drug use (adjusted incidence rate ratios ranged from 1·2 to 2·5 in Europe and from 1·2 to 3·3 in North America). In both regions, individuals with geographical origin other than the region of study generally had lower hospitalisation rates compared with those with geographical origin of the study country. In North America, Indigenous people and Black or African American individuals had higher rates than White individuals (adjusted incidence rate ratios 1·9 and 1·2), whereas Asian and Hispanic people living with HIV had somewhat lower rates. In Europe there was a lower rate in Asian individuals compared with White individuals.

interpretationSubstantial disparities exist in all-cause hospitalisation between demographic groups of people living with HIV in the current cART era in high-income settings, highlighting the need for targeted support.

fundingRoyal Free Charity and the National Institute on Alcohol Abuse and Alcoholism.

Indexed as

HIV InfectionsSexual and Gender MinoritiesCohort StudiesEthnicityEuropeFemaleHomosexuality, MaleHumansMaleNorth America

Identifiers

PMID37777287
PMCPMC10851157

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.