ArticleSaudi medical journal2023
The influence of metoprolol in patients with sepsis-induced cardiomyopathy: A retrospective study.
Article in Saudi medical journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 2 citations in OpenAlex.
- Septic cardiomyopathy: Fact or fiction?American heart journal plus : cardiology research and practice · 2026Review
- Amiodarone-metoprolol co-administration enhances heart rate variability and suppresses inflammatory cytokines in tachyarrhythmia patients.American journal of translational research · 2026Article
- Association between the use of β-adrenergic receptor blockers and all-cause mortality in sepsis-associated rhabdomyolysis syndrome: a cohort study.Frontiers in medicine · 2026Article
- Metoprolol use is associated with improved outcomes in patients with sepsis-induced cardiomyopathy: an analysis of the MIMIC-IV database.BMC cardiovascular disorders · 2024Observational
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
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Abstract
objectivesTo focus on evaluating the clinical influence of metoprolol on sepsis-induced cardiomyopathy (SICM).
methodsA total of 90 patients with SICM was enrolled from December 2018 to February 2021 and divided into 2 groups according to the use of metoprolol during hospitalization in Suzhou Municipal Hospital in Suzhou, China. We compared them with the cardiac function, sequential organ failure assessment score, and clinical outcomes.
resultsBetween the 2 groups, the oxygenation indices and Glasgow coma scale in the metoprolol group were higher on the first day of treatment, with Glasgow coma scale higher on the third day of treatment. However, the doses of norepinephrine in patients with metoprolol showed no significant differences with the control group. The all-causemortality at 28 days in the metoprolol group was lower, and the time of removing from ventilator support as well as the number of failured organs also significantly differed between the 2 groups.
conclusionMetoprolol can reduce the 28-day mortality and shorten the duration of mechanical ventilation in SICM. It can also reduce the number of organ failures and improve the oxygenation index and Glasgow coma scale of these patients. Meanwhile, metoprolol did not affect the norepinephrine dose in patients with SICM.
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