Evidence map›Paper›PMID 37777257›Full record

ArticleJournal of neurointerventional surgery2024

Tigertriever in the treatment of acute ischemic stroke with underlying intracranial atherosclerotic disease.

Diego J Ojeda, Malik Ghannam, Sebastian Sanchez, Mohammad Almajali, Prateeka Koul, Jeffrey L Saver, Rishi Gupta, Santiago Ortega-Gutierrez, David S Liebeskind, Edgar A Samaniego

Open access · hybridAbstract read
In one paragraph

Article in Journal of neurointerventional surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Comparison of mechanical thrombectomy with Tigertriever versus Solitaire X stent retriever in real-world practice: A matched-pair retrospective analysis.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Diego J OjedaDepartment of Neurology, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.
Malik GhannamDepartment of Neurology, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.
Sebastian SanchezDepartment of Neurology, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.
Mohammad AlmajaliDepartment of Neurology, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.
Prateeka KoulDepartment of Neurology, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.
Jeffrey L SaverNeurology and Comprehensive Stroke Center, University of California Los Angeles, Los Angeles, California, USA.ORCID http://orcid.org/0000-0001-9141-2251
Rishi GuptaNeurosurgery, WellStar Medical Group, Marietta, Georgia, USA.
Santiago Ortega-GutierrezDepartments of Neurology, Neurosurgery and Radiology, University of Iowa, Iowa City, Iowa, USA.ORCID http://orcid.org/0000-0002-3408-1297
David S LiebeskindDepartment of Neurology, University of California Los Angeles, Los Angeles, California, USA.
Edgar A SamaniegoDepartments of Neurology, Neurosurgery and Radiology, University of Iowa, Iowa City, Iowa, USA edgarsama@gmail.com.ORCID http://orcid.org/0000-0003-2764-2268
University of Iowa Hospitals and Clinics · USUniversity of California, Los Angeles · USUniversity of Iowa · USWellStar Health System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Tigertriever device offers a unique feature that enables gradual control of the radial expansion. We sought to evaluate the safety and efficacy of the Tigertriever device in patients with large vessel occlusion (LVO) and underlying intracranial atherosclerotic disease (ICAD). The patients were part of the TIGER trial.

methodsThe presence of underlying ICAD was determined by a core imaging laboratory using CT angiography and digital subtraction angiography. The primary outcomes included successful reperfusion, puncture to reperfusion time, and complications associated with the use of the Tigertriever device. Patients underwent mechanical thrombectomy with the Tigertriever device for up to three passes, and alternative devices were employed for subsequent passes.

resultsA total of 160 patients were enrolled in the TIGER trial, and 32 patients had ICAD. Among the patients with ICAD, 78% achieved successful reperfusion within three passes of the Tigertriever device, without requiring rescue therapy. Additionally, a first pass effect was observed in 46.8%. The median time from puncture to reperfusion was 22 minutes. There were no device-related complications. The National Institutes of Health Stroke Scale (NIHSS) score at 24 hours was significantly reduced, from an average of 17 at baseline to 8. At the 3 month follow-up, 50% of patients achieved a modified Rankin Scale score of ≤2.

conclusionEndovascular therapy (EVT) with the Tigertriever device for LVO in patients with underlying ICAD is effective and safe. When compared with historical data from other devices employed in similar cases, we observed a high rate of successful reperfusion, along with a shorter puncture to reperfusion time.

Indexed as

Intracranial ArteriosclerosisIschemic StrokeAgedAged, 80 and overEndovascular ProceduresFemaleHumansMaleMiddle AgedThrombectomyTreatment OutcomeAtherosclerosisStrokeThrombectomy

Identifiers

PMID37777257
PMCPMC11503153
OpenAlexW4387215450

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.