Evidence map›Paper›PMID 37776355›Full record

ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2024

Pulsed-field vs. cryoballoon vs. radiofrequency ablation: a propensity score matched comparison of one-year outcomes after pulmonary vein isolation in patients with paroxysmal atrial fibrillation.

Jens Maurhofer, Thomas Kueffer, Antonio Madaffari, Robin Stettler, Anita Stefanova, Jens Seiler, Gregor Thalmann, Nikola Kozhuharov, Oskar Galuszka, Helge Servatius and 5 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 4 pooled it
11.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 4 syntheses or guidelines pooled it, 52 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pulsed field ablation versus thermal energy ablation for atrial fibrillation: a systematic review and meta-analysis of procedural efficiency, safety, and efficacy.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2024
    Pooled it
  5. Article
  6. Pulsed-field ablation versus thermal ablation in the management of atrial fibrillation: A narrative review.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
    Review
  7. Article
  8. Review
  9. Very high-power short duration radiofrequency ablation to achieve pulmonary vein isolation: the AIR HPSD registry.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
    Article
  10. Review
  11. Review
  12. Controversy: pulsed field ablation is the standard technique for all the candidates for atrial fibrillation ablation.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Review
  13. Pulsed-field ablation beyond pulmonary vein for persistent atrial fibrillation: efficacy and impact on left atrial function.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2025
    Article
  14. Review
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Jens Maurhofer *Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Thomas Kueffer *Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Antonio MadaffariDepartment of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Robin StettlerDepartment of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Anita StefanovaDepartment of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Jens SeilerDepartment of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Gregor ThalmannDepartment of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Nikola KozhuharovDepartment of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Oskar GaluszkaDepartment of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Helge ServatiusDepartment of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Andreas HaeberlinDepartment of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Fabian NotiDepartment of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Hildegard TannerDepartment of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Laurent RotenDepartment of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Tobias ReichlinDepartment of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland. tobias.reichlin@insel.ch.ORCID http://orcid.org/0000-0002-7197-8415
University of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPulsed-field ablation (PFA) has shown favourable data in terms of safety and procedural efficiency for pulmonary vein isolation (PVI). We sought to compare procedural and 1-year follow-up data of patients with paroxysmal atrial fibrillation (AF) undergoing PVI using PFA, cryoballoon ablation (CBA) and radiofrequency ablation (RFA).

methodsConsecutive patients with paroxysmal AF undergoing a first PVI with PFA at our institution were included. For comparison, patients with paroxysmal AF undergoing a first PVI with CBA and RFA were selected using a 1:2:2 propensity score matching. The PFA group followed the standard 32-applications lesion-set protocol, the CBA group a time-to-effect plus 2-min strategy, and the RFA group the CLOSE protocol. Patients were followed with 7d-Holter ECGs 3, 6, and 12 months after ablation. The primary endpoint was recurrence of atrial tachyarrhythmia (ATa) following a blanking period of 3 months.

resultsA total of 200 patients were included (PFA n = 40; CBA n = 80; RFA n = 80). Median procedure times were shortest with CBA (75 min) followed by PFA (94 min) and RFA (182 min; p < 0.001). Fluoroscopy dose was lowest with RFA (1.6Gycm

conclusionIn a propensity score matched analysis of patients with paroxysmal AF, freedom from any ATa 1 year after PVI using PFA was favourable and at least as good as for PVI with CBA or RFA.

Indexed as

Atrial FibrillationCatheter AblationCryosurgeryPulmonary VeinsRadiofrequency AblationHumansPropensity ScoreRecurrenceTreatment OutcomeCryoballoon ablationParoxysmal atrial fibrillationPulmonary vein isolationPulsed-field ablationRadiofrequency ablation

Identifiers

PMID37776355
PMCPMC10902096
OpenAlexW4387220357

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.