Evidence map›Paper›PMID 37776192›Full record

ArticleJournal of the American Heart Association2023

Vertebral Tortuosity Is Associated With Increased Rate of Cardiovascular Events in Vascular Ehlers-Danlos Syndrome.

Sara B Stephens, Sherene Shalhub, Nicholas Dodd, Jesse Li, Michael Huang, Seitaro Oda, Kalyan Kancherla, Tam T Doan, Siddharth K Prakash, Justin D Weigand and 17 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors at 15 institutions in 2 countries.

Sara B StephensDivision of Cardiology, Department of Pediatrics, Baylor College of Medicine Texas Children's Hospital Houston TX USA.ORCID 0000-0002-2180-2198
Sherene ShalhubDivision of Vascular and Endovascular Surgery, Department of Surgery Oregon Health & Science University Portland OR USA.ORCID 0000-0002-8501-2750
Nicholas DoddMemorial Health University Medical Center Savannah GA USA.
Jesse LiDivision of Medical Genetics, Department of Internal Medicine The University of Texas Health Science Center Houston TX USA.
Michael HuangDivision of Medical Genetics, Department of Internal Medicine The University of Texas Health Science Center Houston TX USA.
Seitaro OdaDepartment of Diagnostic Radiology, Faculty of Life Sciences Kumamoto University Kumamoto Japan.ORCID 0000-0003-4101-5113
Kalyan KancherlaNational Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions (GenTAC).
Tam T DoanDivision of Cardiology, Department of Pediatrics, Baylor College of Medicine Texas Children's Hospital Houston TX USA.ORCID 0000-0002-8256-1535
Siddharth K PrakashDivision of Medical Genetics, Department of Internal Medicine The University of Texas Health Science Center Houston TX USA.ORCID 0000-0001-6341-9624
Justin D WeigandDivision of Cardiology, Department of Pediatrics, Baylor College of Medicine Texas Children's Hospital Houston TX USA.ORCID 0000-0002-0016-8140
Federico M AschNational Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions (GenTAC).ORCID 0000-0002-1744-5271
Taylor BeecroftDivision of Cardiology, Department of Pediatrics, Baylor College of Medicine Texas Children's Hospital Houston TX USA.
Alana CecchiDivision of Medical Genetics, Department of Internal Medicine The University of Texas Health Science Center Houston TX USA.ORCID 0000-0002-9588-8705
Teniola ShittuDivision of Cardiology, Department of Pediatrics, Baylor College of Medicine Texas Children's Hospital Houston TX USA.
Liliana PreissRTI International, Research Triangle Park NC USA.
Scott A LeMaireDivision of Cardiothoracic Surgery, Michael E. DeBakey Department of Surgery Baylor College of Medicine Houston TX USA.ORCID 0000-0002-8736-4266
Richard B DevereuxDepartment of Medicine Weill Cornell Medicine New York NY.
Reed E PyeritzDivision of Translational Medicine and Human Genetics Perelman School of Medicine at the University of Pennsylvania PA USA.ORCID 0000-0002-3288-1442
Kathryn W HolmesSection of Cardiology, Department of Pediatrics Oregon Health & Science University and OHSU Doernbecher Children's Hospital Portland OR USA.ORCID 0000-0002-2792-089X
Mary J RomanDepartment of Medicine Weill Cornell Medicine New York NY.ORCID 0000-0003-0183-6769
Ronald V LacroDepartment of Cardiology Boston Children's Hospital Boston MA USA.ORCID 0000-0001-6261-6239
Ralph V ShohetJohn A. Burns School of Medicine Honolulu HI USA.ORCID 0000-0001-5966-6470
Rajesh KrishnamurthyDepartment of Radiology Nationwide Children's Hospital Columbus OH USA.ORCID 0000-0002-9137-642X
Kim EagleNational Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions (GenTAC).
Peter ByersDepartment of Laboratory Medicine and Pathology, Department of Medicine (Medical Genetics) University of Washington Seattle WA USA.ORCID 0000-0001-7786-7030
Dianna M MilewiczDivision of Medical Genetics, Department of Internal Medicine The University of Texas Health Science Center Houston TX USA.ORCID 0000-0002-7806-0068
Shaine A MorrisDivision of Cardiology, Department of Pediatrics, Baylor College of Medicine Texas Children's Hospital Houston TX USA.ORCID 0000-0002-8056-0934
Baylor College of Medicine · USThe University of Texas Health Science Center at Houston · USCornell University · USOregon Health & Science University · USBoston Children's Hospital · USCHI St. Vincent · USKumamoto University · JPMedStar Heart & Vascular Institute · USMemorial Health University Medical Center · USMichigan Medicine · USNationwide Children's Hospital · USRTI International · USUniversity of Hawaiʻi at Mānoa · USUniversity of Pennsylvania · USUniversity of Washington Medical Center · US

Funding

Evaluation of an Imaging Biomarker in Children and Young Adults with AortopathyK23HL127266 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI MORRIS, SHAINE ALAINE · 2015 to 2019
$761k
NHLBI NIH HHS K23 HL127266
6 · The paper itself

Abstract

Background Arterial tortuosity is associated with adverse events in Marfan and Loeys-Dietz syndromes but remains understudied in Vascular Ehlers-Danlos syndrome. Methods and Results Subjects with a pathogenic

Indexed as

Aortic DissectionEhlers-Danlos Syndrome, Type IVLoeys-Dietz SyndromeAdultArteriesFemaleHumansJoint InstabilityMaleMiddle AgedSkin Diseases, GeneticVascular Malformationsarterial rupturecardiovasculardissectiongeneticsVEDS

Identifiers

PMID37776192
PMCPMC10727246
OpenAlexW4387218557

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.