Evidence map›Paper›PMID 37775989›Full record

ArticleJournal of applied clinical medical physics2023

A comprehensive evaluation of advanced dose calculation algorithms for brain stereotactic radiosurgery.

Jihyung Yoon, Hyunuk Jung, Sean M Tanny, Olga Maria Dona Lemus, Michael T Milano, Sara J Hardy, Kenneth Y Usuki, Dandan Zheng

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of applied clinical medical physics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jihyung YoonDepartment of Radiation Oncology, University of Rochester Medical Center, Rochester, New York, USA.
Hyunuk JungDepartment of Radiation Oncology, University of Rochester Medical Center, Rochester, New York, USA.
Sean M TannyDepartment of Radiation Oncology, University of Rochester Medical Center, Rochester, New York, USA.ORCID https://orcid.org/0000-0002-0915-9187
Olga Maria Dona LemusDepartment of Radiation Oncology, University of Rochester Medical Center, Rochester, New York, USA.
Michael T MilanoDepartment of Radiation Oncology, University of Rochester Medical Center, Rochester, New York, USA.
Sara J HardyDepartment of Radiation Oncology, University of Rochester Medical Center, Rochester, New York, USA.
Kenneth Y UsukiDepartment of Radiation Oncology, University of Rochester Medical Center, Rochester, New York, USA.
Dandan ZhengDepartment of Radiation Oncology, University of Rochester Medical Center, Rochester, New York, USA.

Funding

URCC NCORP Research BaseUG1CA189961 · NCI · UNIVERSITY OF ROCHESTER · PI Michelle C Janelsins, KAREN M. MUSTIAN · 2014 to 2026
$67.7M
Clinical and Translational Cancer Control Research Training ProgramT32CA102618 · NCI · UNIVERSITY OF ROCHESTER · PI Michelle C Janelsins, Gary R Morrow · 2019 to 2026
$2.7M
NCI NIH HHS T32 CA102618NCI NIH HHS UG1 CA189961
6 · The paper itself

Abstract

purposeAccurate dose calculation is important in both target and low dose normal tissue regions for brain stereotactic radiosurgery (SRS). In this study, we aim to evaluate the dosimetric accuracy of the two advanced dose calculation algorithms for brain SRS.

methodsRetrospective clinical case study and phantom study were performed. For the clinical study, 138 SRS patient plans (443 targets) were generated using BrainLab Elements Voxel Monte Carlo (VMC). To evaluate the dose calculation accuracy, the plans were exported into Eclipse and recalculated with Acuros XB (AXB) algorithm with identical beam parameters. The calculated dose at the target center (Dref), dose to 95% target volume (D95), and the average dose to target (Dmean) were compared. Also, the distance from the skull was analyzed. For the phantom study, a cylindrical phantom and a head phantom were used, and the delivered dose was measured by an ion chamber and EBT3 film, respectively, at various locations. The measurement was compared with the calculated doses from VMC and AXB.

resultsIn clinical cases, VMC dose calculations tended to be higher than AXB. It was found that the difference in Dref showed > 5% in some cases for smaller volumes < 0.3 cm

conclusionThe two advanced calculation algorithms were extensively compared. For brain SRS, AXB sometimes calculates a noticeable lower target dose for small targets than VMC, and VMC tends to have a slightly closer agreement with measurements than AXB.

Indexed as

RadiosurgeryRadiotherapy, Intensity-ModulatedAlgorithmsBrainHumansRadiotherapy DosageRadiotherapy Planning, Computer-AssistedRetrospective StudiesacurosAXBeclipseelementsMonte CarloSRSVMC

Identifiers

PMID37775989
PMCPMC10647955

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.