Evidence map›Paper›PMID 37774505›Full record

ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2023

Longitudinal Associations Between Higher Self-Reported Energy, Gait Speed, and Cognition in Older Adults With Fatigue.

Rebecca Ehrenkranz, Xiaonan Zhu, Nancy W Glynn, Marnie Bertolet, Sarah B Berman, James B Hengenius, Caterina Rosano

Abstract read
In one paragraph

Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Rebecca EhrenkranzDepartment of Epidemiology, University of Pittsburgh School of Public Health, Pittsburgh, Pennsylvania, USA.ORCID 0000-0003-2810-6045
Xiaonan ZhuDepartment of Epidemiology, University of Pittsburgh School of Public Health, Pittsburgh, Pennsylvania, USA.
Nancy W GlynnDepartment of Epidemiology, University of Pittsburgh School of Public Health, Pittsburgh, Pennsylvania, USA.ORCID 0000-0003-2265-0162
Marnie BertoletDepartment of Epidemiology, University of Pittsburgh School of Public Health, Pittsburgh, Pennsylvania, USA.
Sarah B BermanDepartment of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
James B HengeniusDepartment of Epidemiology, University of Pittsburgh School of Public Health, Pittsburgh, Pennsylvania, USA.ORCID 0000-0003-0662-5282
Caterina RosanoDepartment of Epidemiology, University of Pittsburgh School of Public Health, Pittsburgh, Pennsylvania, USA.ORCID 0000-0002-0909-1506

Funding

Peripheral Nerve Function Decline in an Aged CohortR01AG028050 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI STROTMEYER, ELSA S. · 2007 to 2015
$3.5M
End of Life in the Very OldR01NR012459 · NINR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ALBERT, STEVEN M, LUNNEY, JUNE R · 2011 to 2015
$2.7M
Population Neuroscience of Aging and Alzheimer's Disease (PNA)T32AG055381 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Caterina Rosano, Andrea L Rosso · 2018 to 2026
$2.7M
DYNAMICS OF HEALTH .AGING . AND BODY COMPOSITION /Pittsburgh/-260962101N01AG062101 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · 1996 to 2004
$996k
Epidemiology of the Inverse Comorbidity of Dementia and Cancer: Statistical Methods and Biological MechanismsR03AG070178 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI SHARDELL, MICHELLE DENISE · 2021 to 2021
$309k
HEALTH ABC--COORDINATING UNIT /California/-260062106N01AG062106 · NIA · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · 1996 to 2004
$109k
NIA NIH HHS N01 AG062106NIA NIH HHS N01-AG-6-2101NIA NIH HHS R01 AG028050NIA NIH HHS R03 AG070178NIA NIH HHS T32 AG055381NINR NIH HHS R01 NR012459
6 · The paper itself

Abstract

backgroundOlder adults reporting higher energy levels have better physical function. It is not known if these associations persist among older adults reporting fatigue or if higher energy is associated with cognitive function. We examined longitudinal associations between self-reported energy, gait speed, and cognition, stratified by fatigue, in 2 613 participants (aged 74.6 ± 2.87 years) in the Health, Aging and Body Composition Study.

methodsSelf-reported energy (0-10, dichotomized at median) and fatigue (present/absent) were measured at baseline. Usual and rapid-paced gait speed (m/s), modified Mini-Mental State Examination (3MS), and Digit Symbol Substitution Test (DSST) were measured at baseline and annually over 8 years. Linear mixed effect models compared changes in gait speed, 3MS, and DSST between higher and lower energy groups within fatigue strata.

resultsAt baseline, 724 participants (27%) were fatigued; 240 (33%) coreported higher energy (9% of total). The remaining 1 889 participants were fatigue-free (73%); 1 221 (65%) coreported higher energy (47% of total). Those with fatigue and higher energy had average rapid gait declines of 0.007 m/s per year (p = .04) after adjustment for demographics, comorbidities, depressive symptoms, and exercise. DSST declines were found among only fatigue-free participants (β = 0.17, p = .01). No statistically significant associations with energy were found for fatigue-free participants, or for usual gait or 3MS.

conclusionsAsking about older adults' energy levels as well as fatigue may identify a subgroup of older adults protected against physical and cognitive decline, even among those with fatigue.

Indexed as

CognitionWalking SpeedAgedAgingGaitHumansLongitudinal StudiesSelf ReportHealthy agingMobilityPhysical function

Identifiers

PMID37774505
PMCPMC10692418

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.