Evidence map›Paper›PMID 37773730›Full record

ArticleThe Journal of international medical research2023

Psoriasis paradox-infliximab-induced psoriasis in a patient with Crohn's disease: a case report and mini-review.

Reem Hamdy A Mohammed, Mahmoud Essam, Ismail Anwar, Hany Shehab, Mohamed El Komy

Open access · goldAbstract readCase Reports
In one paragraph

Article in The Journal of international medical research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Reem Hamdy A MohammedDepartment of Rheumatology and Rehabilitation, Kasr-Alainy School of Medicine, Cairo University, Giza, Egypt.ORCID 0000-0003-4994-7687
Mahmoud EssamIntegrated Unit for Research in Intestinal Disorders, Department of Tropical Medicine, Hepatogastroenterology and Infectious Diseases, Kasr-Alainy School of Medicine, Cairo University, Giza, Egypt.
Ismail AnwarIntegrated Unit for Research in Intestinal Disorders, Department of Tropical Medicine, Hepatogastroenterology and Infectious Diseases, Kasr-Alainy School of Medicine, Cairo University, Giza, Egypt.
Hany ShehabIntegrated Unit for Research in Intestinal Disorders, Department of Tropical Medicine, Hepatogastroenterology and Infectious Diseases, Kasr-Alainy School of Medicine, Cairo University, Giza, Egypt.
Mohamed El KomyIntegrated Unit for Research in Intestinal Disorders, Department of Tropical Medicine, Hepatogastroenterology and Infectious Diseases, Kasr-Alainy School of Medicine, Cairo University, Giza, Egypt.
Cairo University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biologic drugs are therapeutic modalities designed to inhibit specific cytokine signaling pathways. The introduction of these drugs in the management of autoimmune diseases has dramatically changed the treatment paradigm of chronic systemic immune-mediated inflammatory disorders. However, despite their overall acceptable safety profiles, paradoxical reactions have been reported in some real-life cases including case studies and clinical trials. In this study, we report a patient with Crohn's disease who developed infliximab-induced psoriasis vulgaris after starting infliximab treatment. In this case, infliximab was discontinued, and low-dose steroids and subcutaneous methotrexate were introduced to control both his psoriasis and bowel condition with satisfying responses.

Indexed as

Autoimmune DiseasesCrohn DiseasePsoriasisHumansInfliximabMethotrexateInfliximabMethotrexateBiologicsCrohn’s diseaseinflammatory bowel diseaseinfliximabmethotrexatepsoriasis paradoxsteroid

Identifiers

PMID37773730
PMCPMC10541761
OpenAlexW4387166374

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.